{"id":"W4412710692","doi":"10.1093/jac/dkaf212","title":"Hypertension and blood pressure changes with dolutegravir or comparator antiretroviral therapy in randomized trials through 96 weeks","year":2025,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"GlaxoSmithKline (Canada)","funders":"ViiV Healthcare; Gilead Sciences","keywords":"Dolutegravir; Medicine; Blood pressure; Integrase inhibitor; Internal medicine; Randomized controlled trial; Adverse effect; Clinical trial; Post-hoc analysis; Antiretroviral therapy; Human immunodeficiency virus (HIV); Viral load; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02216846,0.001276719,0.004264094,0.0009698721,0.0005275498,0.00212882,0.0008034012,0.001816191,0.00555167],"category_scores_gemma":[0.02612173,0.0008234835,0.007955741,0.001368925,0.001259484,0.001940588,0.0008337089,0.002304459,0.0004129904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000912375,"about_ca_system_score_gemma":0.00190856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000490039,"about_ca_topic_score_gemma":0.001320602,"domain_scores_codex":[0.9750131,0.0184625,0.00348247,0.001478475,0.001021787,0.0005416834],"domain_scores_gemma":[0.9822525,0.01014677,0.005474017,0.0008519254,0.0006894711,0.0005853428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9352047,0.00095705,0.003297559,0.008243456,0.03222328,0.00005068236,0.000079554,0.0004350567,0.0008982468,0.0002287251,0.0005212626,0.01786027],"study_design_scores_gemma":[0.9044382,0.04633733,0.009167568,0.001519862,0.03345937,0.00008360043,0.000081772,0.0008287639,0.0007110626,0.0009686371,0.002363105,0.00004073586],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8252613,0.1329498,0.006427533,0.002255753,0.002527362,0.02055834,0.003796207,0.0002857009,0.00593798],"genre_scores_gemma":[0.9606743,0.01269445,0.005055045,0.0009111215,0.0005587609,0.01773177,0.0009804652,0.00003292748,0.001361172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02216846,"threshold_uncertainty_score":0.1172394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0423366623893777,"score_gpt":0.338603472322464,"score_spread":0.2962668099330862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}