{"id":"W4412720811","doi":"10.1371/journal.pone.0329074","title":"Sequential islet transplants for type 1 diabetes are not associated with sustained or cumulative increases in hepatic portal venous pressure","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Islet; Portal venous pressure; Islet cell transplantation; Liver transplantation; Central venous pressure; Transplantation; Type 2 diabetes; Blood pressure; Internal medicine; Diabetes mellitus; Insulin; Gastroenterology; Endocrinology; Cardiology; Portal hypertension; Cirrhosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009906613,0.000184585,0.0003029962,0.0002170058,0.0001340238,0.0005427607,0.0001808073,0.0001735489,0.001069217],"category_scores_gemma":[0.003661495,0.0001896577,0.0004074733,0.0003638389,0.0004311565,0.0002380959,0.000381277,0.0005845496,0.0001110938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000347716,"about_ca_system_score_gemma":0.0004705272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003005426,"about_ca_topic_score_gemma":0.004782173,"domain_scores_codex":[0.9992441,0.0002063399,0.00005902279,0.000162342,0.000219861,0.0001083699],"domain_scores_gemma":[0.9953405,0.001699352,0.00223044,0.0003349414,0.0001025459,0.000292223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001565548,0.00006837838,0.9845681,0.00002529108,0.0001677247,0.0001411265,0.00009021867,0.0002342736,0.002116682,0.00003558972,0.00004402958,0.01094299],"study_design_scores_gemma":[0.000007947557,0.0006772011,0.9977959,0.000003576404,0.00006129323,0.0002772263,0.00005387768,0.0005620754,0.0004617163,0.00002857092,0.00006770393,0.000002906509],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991795,0.0003281289,0.000301226,0.00001832549,0.000003085909,0.000002990777,0.00003952357,0.000005592199,0.0001215114],"genre_scores_gemma":[0.9996283,0.00007622769,0.0001375687,0.000006540168,0.000006191918,0.00000179519,0.00006381289,0.000001957496,0.0000776173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003005426,"threshold_uncertainty_score":0.005975842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05003916870818707,"score_gpt":0.2748064810572331,"score_spread":0.224767312349046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}