{"id":"W4412728195","doi":"10.1016/j.eclinm.2025.103365","title":"Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort study","year":2025,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Medicine; Cohort; Liver transplantation; Chronic hepatitis; Cohort study; Liver failure; Internal medicine; Prognostic model; Intensive care medicine; Emergency medicine; Overall survival; Transplantation; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006309873,0.0001999227,0.0005838926,0.0002091352,0.00007195755,0.000009145071,0.00009517928,0.0001074233,0.00002708842],"category_scores_gemma":[0.0005159316,0.0001601406,0.00007116409,0.0002234141,0.00006272849,0.00005253618,0.00002514135,0.0001569232,0.000002650864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007904447,"about_ca_system_score_gemma":0.0003342304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005845858,"about_ca_topic_score_gemma":0.0003053331,"domain_scores_codex":[0.9980319,0.0000275058,0.000881576,0.0004263461,0.0004339437,0.0001987532],"domain_scores_gemma":[0.9985594,0.000531026,0.0001445474,0.0002716579,0.0003426291,0.000150705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006149944,0.001120396,0.9939718,0.0007668119,0.0006535458,0.00001309174,0.001126639,0.00005614006,0.0005146587,0.0003500921,0.0001772745,0.0006345401],"study_design_scores_gemma":[0.008195845,0.002165476,0.974713,0.000963212,0.002042205,0.000004460175,0.0001302472,0.006373949,0.005132045,0.00002006905,0.0001048293,0.0001547023],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9131967,0.00003400685,0.0801652,0.001372204,0.0001095264,0.00477378,0.0001725159,0.00008981553,0.00008620976],"genre_scores_gemma":[0.9643192,0.0002692865,0.03371441,0.0007729953,0.00005726725,0.0003455679,0.0002805416,0.00001966019,0.000221041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05112249,"threshold_uncertainty_score":0.6530345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0322090646698283,"score_gpt":0.3571445069349668,"score_spread":0.3249354422651385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}