{"id":"W4412779753","doi":"10.3324/haematol.2025.288227","title":"Recurrence of minimal residual disease in acute myeloid leukemia: a window of opportunity for intervention","year":2025,"lang":"en","type":"article","venue":"Haematologica","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Minimal residual disease; Myeloid leukemia; Medicine; Residual; Window of opportunity; Intervention (counseling); Therapeutic window; Disease; Internal medicine; Oncology; Leukemia; Pediatrics; Computer science; Psychiatry; Algorithm; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009240945,0.0001301129,0.0004932632,0.0002269735,0.0004056248,0.001640781,0.0003789632,0.0007476542,0.002122885],"category_scores_gemma":[0.004304388,0.00008781638,0.0002804791,0.0001522599,0.0005546242,0.001165098,0.0004964605,0.001572609,0.0003083648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005640674,"about_ca_system_score_gemma":0.0007724241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003859344,"about_ca_topic_score_gemma":0.0008252217,"domain_scores_codex":[0.9995105,0.0001674983,0.00004071722,0.00004568783,0.0000716471,0.0001639479],"domain_scores_gemma":[0.9984947,0.0007634623,0.0002947731,0.00006050876,0.00008708119,0.0002994745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00681238,0.0009940382,0.1407472,0.0008872572,0.0002181146,0.0275202,0.002142038,0.001400302,0.01436828,0.0356337,0.02697497,0.7423015],"study_design_scores_gemma":[0.001075902,0.01412161,0.4209684,0.003911329,0.0009054084,0.1583485,0.0125253,0.008294017,0.01369494,0.08839682,0.2774428,0.0003149551],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7500129,0.1305699,0.008543897,0.06898608,0.001554779,0.0001239456,0.0002660957,0.0002164564,0.03972596],"genre_scores_gemma":[0.9893266,0.005737389,0.0007757337,0.001724839,0.001389815,0.00002130475,0.00009336823,0.00001418093,0.0009168492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002122885,"threshold_uncertainty_score":0.007101715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04320646628438361,"score_gpt":0.3539262646695517,"score_spread":0.3107197983851681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}