{"id":"W4412785718","doi":"10.1093/sleep/zsaf212","title":"Genome-wide gene by sleepiness interaction analysis for sleep apnea","year":2025,"lang":"en","type":"article","venue":"SLEEP","topic":"Obstructive Sleep Apnea Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Minority Health and Health Disparities; National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; National Eye Institute; University of North Carolina; National Institute on Aging; University of Illinois at Chicago; San Diego State University; Jackson State University; National Institute of Neurological Disorders and Stroke; Albert Einstein College of Medicine, Yeshiva University; Mississippi State Department of Health; University of Miami; U.S. Department of Health and Human Services; National Institutes of Health; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Ontario Institute for Cancer Research","keywords":"Sleep apnea; Obstructive sleep apnea; Candidate gene; Genome-wide association study; Medicine; Gene interaction; Genetics; Bioinformatics; Gene; Biology; Internal medicine; Genotype; Single-nucleotide polymorphism","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006009412,0.001458951,0.002489257,0.002392824,0.0008228586,0.001308327,0.001297727,0.0009843699,0.004103418],"category_scores_gemma":[0.008105617,0.0004918126,0.01262164,0.003580794,0.0004534865,0.0004633121,0.001331995,0.001595858,0.0002490684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004988615,"about_ca_system_score_gemma":0.001134624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005689524,"about_ca_topic_score_gemma":0.007067692,"domain_scores_codex":[0.9935862,0.003021917,0.0005319006,0.00191599,0.0005732369,0.0003706401],"domain_scores_gemma":[0.9920106,0.005717035,0.0007864017,0.0008851572,0.0003236071,0.0002772782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01059362,0.0001909598,0.7151644,0.001928655,0.2346991,0.001329536,0.0002490827,0.002199529,0.01037857,0.0006420729,0.002386528,0.02023798],"study_design_scores_gemma":[0.001232786,0.00232416,0.7725794,0.0001901213,0.1981378,0.001500331,0.000297854,0.01310602,0.003206385,0.001866736,0.005444095,0.0001142214],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9236384,0.03471978,0.02683409,0.001225685,0.0004769862,0.0002331208,0.01043707,0.0006922908,0.001742519],"genre_scores_gemma":[0.9900846,0.001025176,0.005788952,0.0002012117,0.00008849602,0.0002349271,0.001974905,0.00006659828,0.0005351866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006009412,"threshold_uncertainty_score":0.0317812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612227548841559,"score_gpt":0.3145924645533625,"score_spread":0.2984701890649469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}