{"id":"W4412790523","doi":"10.1016/j.xcrm.2025.102260","title":"High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis","year":2025,"lang":"en","type":"article","venue":"Cell Reports Medicine","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; St. Michael's Hospital","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research; Yunnan Provincial Science and Technology Department; National Natural Science Foundation of China; Chinese Academy of Sciences; Kunming Science and Technology Bureau","keywords":"Bacteroides thetaiotaomicron; Palmitic acid; Bacteroides; Food science; Biology; Microbiology; Biochemistry; Fatty acid; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510258,0.0002717172,0.0002247556,0.0002038985,0.000134636,0.0002599856,0.00007946799,0.000236426,0.001295589],"category_scores_gemma":[0.0001403362,0.0001108084,0.0002264208,0.0001105015,0.0001612777,0.0001386997,0.0002606299,0.0004913147,0.0001910331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001641676,"about_ca_system_score_gemma":0.0001898903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003329755,"about_ca_topic_score_gemma":0.0004731119,"domain_scores_codex":[0.9998949,0.00003063801,0.000006754617,0.00002199944,0.00001535126,0.00003029711],"domain_scores_gemma":[0.99991,0.000008745709,0.00002616877,0.000007205065,0.00000843754,0.00003932806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001195261,0.0001133478,0.002485775,0.00003761938,0.00001684335,0.00008482963,0.00002668934,0.00002015415,0.9936733,0.00004726544,0.000060028,0.002239004],"study_design_scores_gemma":[0.0002520165,0.005337694,0.1787378,0.00005966528,0.0001736287,0.00101375,0.0004807251,0.00176535,0.8064941,0.0004608307,0.005197958,0.00002650531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971432,0.0008653033,0.001193093,0.0001606153,0.00003685772,0.00001300198,0.00008050742,0.00002689357,0.0004805723],"genre_scores_gemma":[0.9978935,0.0004073896,0.0007251083,0.0001087624,0.00001146737,0.00001724355,0.00006974063,0.000006993854,0.0007597993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001295589,"threshold_uncertainty_score":0.004334211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008243446406318803,"score_gpt":0.263650627502368,"score_spread":0.2554071810960492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}