{"id":"W4412790523","doi":"10.1016/j.xcrm.2025.102260","title":"High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis","year":2025,"lang":"en","type":"article","venue":"Cell Reports Medicine","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; St. Michael's Hospital","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research; Yunnan Provincial Science and Technology Department; National Natural Science Foundation of China; Chinese Academy of Sciences; Kunming Science and Technology Bureau","keywords":"Bacteroides thetaiotaomicron; Palmitic acid; Bacteroides; Food science; Biology; Microbiology; Biochemistry; Fatty acid; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004024072,0.0002734115,0.000413363,0.00008541827,0.0001598619,0.00002024726,0.0001469659,0.0001584539,0.0001049857],"category_scores_gemma":[0.0003762855,0.0002229615,0.00007093317,0.0001869675,0.00009859978,0.000004680073,0.0001450258,0.0001384611,0.00001058496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005100128,"about_ca_system_score_gemma":0.0001411021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003848555,"about_ca_topic_score_gemma":0.00002451573,"domain_scores_codex":[0.9980221,0.000063857,0.0005993043,0.0007457432,0.0001449344,0.0004240679],"domain_scores_gemma":[0.9986715,0.00001528874,0.0002335926,0.0007576524,0.0001332841,0.0001886768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003939849,0.000104347,0.005171948,0.0001887964,0.00004404256,0.0000295618,0.00008261675,0.000002461913,0.9545901,0.000004652155,0.03912978,0.0006123111],"study_design_scores_gemma":[0.0004700287,0.0005467872,0.01368049,0.0002951853,0.00009451962,0.00004456954,0.00008928137,0.000001671805,0.9609624,0.00005528761,0.02352436,0.000235429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937316,0.001739565,0.000178719,0.001943495,0.0004785958,0.0006582356,0.00001023488,0.00003628005,0.001223279],"genre_scores_gemma":[0.9947917,0.0001733152,0.0003471048,0.001656861,0.0003572612,0.00003605544,0.0003752509,0.00003311959,0.002229259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01560542,"threshold_uncertainty_score":0.9092107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008243446406318803,"score_gpt":0.263650627502368,"score_spread":0.2554071810960492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}