{"id":"W4412790526","doi":"10.1261/rna.080414.125","title":"Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs","year":2025,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta; University of Lethbridge","funders":"","keywords":"Signal recognition particle RNA; Signal recognition particle; Biology; RNA; Small nuclear RNA; Protein secondary structure; RNA polymerase II; Computational biology; Cell biology; RNA-binding protein; Biophysics; Non-coding RNA; Ribosome; Genetics; Biochemistry; Gene expression; Gene; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000493664,0.00006067485,0.00008985644,0.00002214264,0.00004347369,0.000006227449,0.00003239861,0.00006908434,0.000001687659],"category_scores_gemma":[0.00005331967,0.00005170087,0.00001758776,0.00002952458,0.00006202056,0.000002906592,0.00005651394,0.00002182651,1.691583e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003331248,"about_ca_system_score_gemma":0.00001048242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003874859,"about_ca_topic_score_gemma":0.00000603159,"domain_scores_codex":[0.9996662,0.00002525159,0.00007772999,0.0001303532,0.00003890659,0.00006160775],"domain_scores_gemma":[0.9998183,0.000009421487,0.00003622786,0.00008481175,0.00003700819,0.0000142382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001955073,0.000005780534,0.00008104192,0.0000476462,0.00002466275,2.740307e-7,0.00003237113,4.329987e-7,0.9484309,0.0004443131,0.00006620214,0.05084681],"study_design_scores_gemma":[0.0001257602,0.00008872796,0.001388891,0.00002866005,0.00002169202,0.0000019108,0.00005057469,0.00007290376,0.994775,0.0025832,0.0008105455,0.00005213691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953461,0.002529766,0.001671976,0.0001513624,0.00006684061,0.00007798227,0.000007442822,0.000003148923,0.0001453747],"genre_scores_gemma":[0.9982941,0.0004931404,0.0008887136,0.00004472643,0.00004315547,0.000003984486,0.000005050711,0.000003281406,0.0002239121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05079468,"threshold_uncertainty_score":0.21083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01086667733554218,"score_gpt":0.277235837896215,"score_spread":0.2663691605606728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}