{"id":"W4412828528","doi":"10.1021/acscatal.5c03724","title":"Remote Asymmetric Induction via a Chiral Acetylene Equivalent","year":2025,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Synthesis and Properties of Aromatic Compounds","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Heinrich-Heine-Universität Düsseldorf; Deutsche Forschungsgemeinschaft; Natural Sciences and Engineering Research Council of Canada; Universität Heidelberg; University of Toronto; Baden-Württemberg Stiftung; Forschungszentrum Jülich; Merck","keywords":"Asymmetric induction; Acetylene; Catalysis; Chemistry; Enantioselective synthesis; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404623,0.0004337284,0.0001950324,0.0002971293,0.0002043258,0.0003564366,0.0004230838,0.0002208309,0.004448196],"category_scores_gemma":[0.0002158249,0.0001421029,0.0002190042,0.0002058254,0.0002957997,0.0003907011,0.000529032,0.0008769103,0.0018039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666748,"about_ca_system_score_gemma":0.000422345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003245423,"about_ca_topic_score_gemma":0.0006911199,"domain_scores_codex":[0.999799,0.00001757412,0.00001787039,0.00004562951,0.00005946643,0.00006055995],"domain_scores_gemma":[0.9998757,0.00001580339,0.00002689881,0.00003178475,0.00002183632,0.00002794069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000128958,0.00006888893,0.0002557889,0.000145037,0.0000104409,0.0005351505,0.00006708664,0.0003149133,0.9799088,0.006959263,0.0003101981,0.01129559],"study_design_scores_gemma":[0.00001025782,0.0001349865,0.0002195373,0.000005002683,0.000007259242,0.0002534707,0.000008959943,0.0004330971,0.9906907,0.0001868375,0.008043933,0.000006013579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8632045,0.001808042,0.04217684,0.0005563747,0.0003012417,0.0001701246,0.0008713093,0.0005373341,0.09037432],"genre_scores_gemma":[0.9837266,0.0006934895,0.006406605,0.00008585928,0.00004032284,0.00003213278,0.0002685515,0.00004960939,0.008696727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004448196,"threshold_uncertainty_score":0.01488072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01468146853007071,"score_gpt":0.2444148355244975,"score_spread":0.2297333669944268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}