{"id":"W4412828528","doi":"10.1021/acscatal.5c03724","title":"Remote Asymmetric Induction via a Chiral Acetylene Equivalent","year":2025,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Synthesis and Properties of Aromatic Compounds","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Heinrich-Heine-Universität Düsseldorf; Deutsche Forschungsgemeinschaft; Natural Sciences and Engineering Research Council of Canada; Universität Heidelberg; University of Toronto; Baden-Württemberg Stiftung; Forschungszentrum Jülich; Merck","keywords":"Asymmetric induction; Acetylene; Catalysis; Chemistry; Enantioselective synthesis; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001903887,0.0001742145,0.0002801394,0.0002385471,0.0001562417,0.00006529318,0.0003374592,0.0001190159,0.000428743],"category_scores_gemma":[0.0001690056,0.0001533419,0.0001780506,0.0007358265,0.00004578019,0.0001142225,0.0001929028,0.0001467123,0.0001064884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00013348,"about_ca_system_score_gemma":0.00004105339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003421463,"about_ca_topic_score_gemma":0.00001401007,"domain_scores_codex":[0.9988304,0.00001907293,0.0003257399,0.0003294558,0.0002481398,0.0002471983],"domain_scores_gemma":[0.9989824,0.0001028206,0.0001021175,0.0006999684,0.00005675882,0.00005594539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003438072,0.00009768629,0.0006399514,0.0001423132,0.0004226571,0.0000033258,0.0001629687,0.00002244289,0.1013558,0.0000562314,0.002467692,0.8945946],"study_design_scores_gemma":[0.0006896215,0.00004008535,0.001904908,0.0002141595,0.0006787083,0.0000207515,0.000319354,0.0037119,0.9629087,0.002630966,0.02634776,0.0005331043],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9090562,0.001075651,0.001272126,0.001103165,0.0002414577,0.00005487204,0.000004886,0.000149171,0.08704247],"genre_scores_gemma":[0.9865911,0.00009744163,0.00111736,0.0001178752,0.000183264,0.000009709308,0.00004981918,0.00001605721,0.01181738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8940615,"threshold_uncertainty_score":0.6253101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01468146853007071,"score_gpt":0.2444148355244975,"score_spread":0.2297333669944268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}