{"id":"W4412836990","doi":"10.1038/s41380-025-03105-x","title":"The habenula in mood disorders: A systematic review of human studies","year":2025,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"HEC Montréal; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Psychology; Mood; Mood disorders; Habenula; Human studies; Neuroscience; Psychiatry; Psychotherapist; Medicine; Central nervous system; Anxiety; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003452616,0.001232084,0.004573749,0.008629814,0.0004852053,0.001839855,0.001515086,0.001430176,0.005102197],"category_scores_gemma":[0.01419942,0.0007252023,0.004538059,0.0087812,0.0006050593,0.001479951,0.001265461,0.0007812309,0.0004675261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001987681,"about_ca_system_score_gemma":0.006921563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006571399,"about_ca_topic_score_gemma":0.02172587,"domain_scores_codex":[0.9975846,0.0006660216,0.0009798547,0.0002507444,0.0004158925,0.0001028245],"domain_scores_gemma":[0.990807,0.00664158,0.001515947,0.0001381373,0.0007795551,0.0001176958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001233224,0.00001016438,0.0005014289,0.9186769,0.003346687,0.000143849,0.0001390124,0.00009029602,0.0002032248,0.0003235545,0.002376532,0.0740649],"study_design_scores_gemma":[0.000126161,0.0001595029,0.004535364,0.9071074,0.03556525,0.0008533976,0.0002497689,0.0000576715,0.0001900645,0.0005029316,0.0506196,0.00003295702],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002815976,0.9991196,0.00006649397,0.00009304153,0.00005192585,0.00004659111,0.0001639316,0.000003069874,0.000173839],"genre_scores_gemma":[0.003612211,0.9956683,0.0002359799,0.0001799106,0.00003711666,0.00008775853,0.0001129016,0.000001962857,0.00006397759],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008629814,"threshold_uncertainty_score":0.01825941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03726802640726633,"score_gpt":0.3897541094059538,"score_spread":0.3524860829986875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}