{"id":"W4412867389","doi":"10.3390/toxics13080636","title":"Exposure–Response Relationship of Toxic Metal(loid)s in Mammals: Their Bioinorganic Chemistry in Blood Is an Intrinsic Component of the Selectivity Filters That Mediate Organ Availability","year":2025,"lang":"en","type":"review","venue":"Toxics","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Sorbonne Université","keywords":"Bioinorganic chemistry; Detoxification (alternative medicine); Chemistry; Physiology; Biology; Environmental chemistry; Biochemistry; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005395516,0.0008329969,0.001383542,0.001802255,0.0002119169,0.0009650863,0.0007636466,0.001025711,0.002678609],"category_scores_gemma":[0.0007986245,0.0002553424,0.0006877374,0.001756062,0.0004193618,0.0007748518,0.0004769019,0.0009887363,0.001046593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006298685,"about_ca_system_score_gemma":0.001148386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00185523,"about_ca_topic_score_gemma":0.002540501,"domain_scores_codex":[0.9997866,0.00004524407,0.00003393262,0.00004394818,0.00007129094,0.00001899766],"domain_scores_gemma":[0.9997079,0.0001550955,0.0000469329,0.00000918868,0.00006693981,0.00001389092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001398192,0.0000961672,0.0006280944,0.06323176,0.0003430339,0.0003078065,0.0001670516,0.0009754193,0.005441667,0.007934676,0.02005574,0.9006787],"study_design_scores_gemma":[0.00001723478,0.0002159627,0.002844173,0.007186103,0.0004025531,0.001737198,0.0001474163,0.0002212902,0.001711576,0.00326892,0.982217,0.00003057146],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002490419,0.9980989,0.0001772782,0.0002124634,0.0001298608,0.000005909037,0.00002956692,0.000007064345,0.001089856],"genre_scores_gemma":[0.001846618,0.9970693,0.0001706239,0.0001387841,0.00009177376,0.000009961182,0.00002708523,0.000001348982,0.0006445637],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002678609,"threshold_uncertainty_score":0.008960843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04109940349169967,"score_gpt":0.2724867512025511,"score_spread":0.2313873477108515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}