{"id":"W4412884609","doi":"10.1111/ene.70231","title":"Improvement in Patient‐Reported Symptoms of Generalised Myasthenia Gravis With Rozanolixizumab in the Randomised Phase 3 MycarinG Study Using the MG Symptoms PRO","year":2025,"lang":"en","type":"article","venue":"European Journal of Neurology","topic":"Myasthenia Gravis and Thymoma","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Janssen Pharmaceuticals; Genentech; Grifols; Sanofi Genzyme; Sarepta Therapeutics; Mitsubishi Tanabe Pharma Corporation; UCB; Alexion Pharmaceuticals; Biogen; Regeneron Pharmaceuticals; Sanofi; Amgen","keywords":"Medicine; Myasthenia gravis; Placebo; Muscle weakness; Weakness; Physical therapy; Activities of daily living; Rasch model; Post-hoc analysis; Internal medicine; Surgery; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005255949,0.0009514377,0.002224528,0.0003036764,0.0002945951,0.0008272392,0.0006844664,0.001172719,0.003155221],"category_scores_gemma":[0.001927657,0.000451538,0.00179711,0.0003217981,0.0007829962,0.0007046651,0.0004231102,0.002164107,0.0006281249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006028016,"about_ca_system_score_gemma":0.0008919299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004499104,"about_ca_topic_score_gemma":0.001624477,"domain_scores_codex":[0.9981179,0.001277484,0.0001224073,0.000153918,0.0001608664,0.0001673641],"domain_scores_gemma":[0.9988388,0.0002946937,0.0004022484,0.0001154805,0.00008274774,0.0002660133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9139108,0.01071811,0.004738695,0.001279029,0.002632878,0.00009114908,0.0001711298,0.0008568906,0.01655887,0.000139872,0.001178666,0.0477238],"study_design_scores_gemma":[0.7104212,0.2646955,0.02100524,0.00005066147,0.0008388659,0.0001185865,0.0000326652,0.0003729344,0.001121005,0.0001190425,0.001193424,0.00003098442],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918423,0.003241404,0.0004707926,0.0002648188,0.0001044243,0.002271822,0.000693864,0.00009300369,0.001017609],"genre_scores_gemma":[0.9927928,0.001107294,0.0009231372,0.0004856109,0.0001242131,0.002896712,0.0007796091,0.00001649735,0.0008741447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005255949,"threshold_uncertainty_score":0.02779645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01969143814509447,"score_gpt":0.2827815193639654,"score_spread":0.2630900812188709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}