{"id":"W4412884615","doi":"10.1364/boe.568368","title":"Polar organization of H&E dyes in histology tissue revealed by polarimetric nonlinear microscopy","year":2025,"lang":"en","type":"article","venue":"Biomedical Optics Express","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Saint Mary's University","funders":"National Research Council Canada; Lietuvos Mokslo Taryba; Canada Foundation for Innovation; Research Nova Scotia; Saint Mary’s University","keywords":"Histology; Microscopy; Polarimetry; Optical microscope; Optics; Biophysics; Chemistry; Biology; Materials science; Pathology; Medicine; Physics; Scanning electron microscope","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002742088,0.0002939033,0.00009477281,0.0004642772,0.0002516574,0.0004082873,0.0001635391,0.0002676808,0.001650544],"category_scores_gemma":[0.0004120252,0.0003007723,0.00006523164,0.0002860648,0.0006167422,0.0004305497,0.00030258,0.0003645296,0.0004275338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00025263,"about_ca_system_score_gemma":0.0002443085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005871337,"about_ca_topic_score_gemma":0.0007301422,"domain_scores_codex":[0.9998482,0.00004060055,0.000006114347,0.00003585379,0.0000440084,0.00002521097],"domain_scores_gemma":[0.9997063,0.0001032397,0.00006955479,0.00002853067,0.00006319503,0.00002913192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003962441,0.000005837399,0.0002965656,0.00001731967,0.000001367636,0.00003532944,0.00002758285,0.00009344605,0.9978847,0.0002635846,0.00001185855,0.001322792],"study_design_scores_gemma":[0.00001153041,0.0001194257,0.01286545,0.00001174445,0.00001094755,0.0003260106,0.0001559366,0.003585299,0.9811644,0.0004265746,0.001311249,0.00001133327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9443587,0.0006994601,0.0481973,0.00009607351,0.00001642702,0.0000409785,0.000138013,0.0001435308,0.0063095],"genre_scores_gemma":[0.9504018,0.001019854,0.04284221,0.00009006446,0.00001896977,0.00007794282,0.0001555786,0.00006947923,0.005324175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001650544,"threshold_uncertainty_score":0.005521595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004663652348448126,"score_gpt":0.2956440139762655,"score_spread":0.2909803616278174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}