{"id":"W4412885342","doi":"10.1093/brain/awaf286","title":"Haematopoietic stem cell transplant versus immune-reconstitution therapy in relapsing multiple sclerosis","year":2025,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré de Santé et Services Sociaux de Chaudière-Appalache; St. Michael's Hospital; Ottawa Hospital; Cegep de Saint Jerome; University of Ottawa","funders":"Ms. Foundation for Women; National Health and Medical Research Council; Multiple Sclerosis Australia","keywords":"Alemtuzumab; Cladribine; Medicine; Expanded Disability Status Scale; Multiple sclerosis; Internal medicine; Hematopoietic stem cell transplantation; Stem cell; Transplantation; Oncology; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000528044,0.0001877826,0.0003999232,0.0003175713,0.0001572933,0.00002981752,0.0001298778,0.000113752,0.00005220625],"category_scores_gemma":[0.0001752546,0.0001648848,0.0001381485,0.0004773555,0.0001808562,0.00009008524,0.00004438976,0.0003149356,0.00004177993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153385,"about_ca_system_score_gemma":0.0002224832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002849455,"about_ca_topic_score_gemma":0.0002774194,"domain_scores_codex":[0.9984314,0.0001426514,0.0003981964,0.0003445838,0.0002747065,0.0004084411],"domain_scores_gemma":[0.9987479,0.0007215164,0.00004987947,0.0003434665,0.00005956128,0.00007762018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0061167,0.0009827113,0.06869467,0.0007080546,0.0002977453,0.0001002261,0.004805634,0.0001370197,0.7298666,0.0007437429,0.00420156,0.1833454],"study_design_scores_gemma":[0.06693856,0.000890024,0.6619237,0.006312868,0.00009354922,0.00001448802,0.003570252,0.006544842,0.2399688,0.00006596853,0.01294747,0.0007294366],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823019,0.003648092,0.0004881474,0.003730451,0.0004894069,0.0009877553,0.00001751766,0.0001012779,0.008235445],"genre_scores_gemma":[0.9959798,0.002353928,0.0003121061,0.0002371856,0.00003302141,0.00008456193,0.00001713607,0.00001581661,0.0009663802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5932291,"threshold_uncertainty_score":0.6723809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08276729039664442,"score_gpt":0.306380828420845,"score_spread":0.2236135380242006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}