{"id":"W4412904563","doi":"10.21203/rs.3.rs-7049957/v1","title":"CD11b-positive macrophages among human E-MNCs attenuate cellular senescence and promote tissue regeneration in radiation-damaged salivary glands","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Japan Society for the Promotion of Science","keywords":"Regeneration (biology); Senescence; Cell biology; Salivary gland; Cellular senescence; Immunology; Biology; Phenotype; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003160275,0.0002630787,0.0002899424,0.0002264469,0.000167297,0.0003325983,0.0001219477,0.0003306548,0.002427169],"category_scores_gemma":[0.0001824771,0.0001426779,0.000232577,0.0001303255,0.0001557659,0.0001862775,0.0002530089,0.0005237295,0.0005642785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008033813,"about_ca_system_score_gemma":0.0001316286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002643651,"about_ca_topic_score_gemma":0.0002996932,"domain_scores_codex":[0.9998035,0.00005466695,0.00001813186,0.00004355688,0.00002739046,0.00005283043],"domain_scores_gemma":[0.9999154,0.00001770285,0.00001518864,0.00001537404,0.00001681179,0.00001955392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009928226,0.0001265282,0.0008221522,0.00005855478,0.00001221302,0.000056656,0.00005241488,0.00007361517,0.9937145,0.0001439047,0.00007183543,0.003874817],"study_design_scores_gemma":[0.0001432946,0.001161049,0.01023791,0.00002649271,0.0001050939,0.000375199,0.000198465,0.001088489,0.980808,0.0001419852,0.005705073,0.000008926451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966,0.0007747295,0.00161532,0.0000536674,0.00004517943,0.00002432426,0.00008744471,0.00002123183,0.0007782247],"genre_scores_gemma":[0.9939935,0.0004926923,0.001365907,0.00006579136,0.00002822361,0.00004725722,0.0001938513,0.00001664626,0.003796177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002427169,"threshold_uncertainty_score":0.008119643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03203072677988519,"score_gpt":0.3733188065556157,"score_spread":0.3412880797757305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}