{"id":"W4412914018","doi":"10.3390/curroncol32080418","title":"BCMA CAR-T: From Multiple Myeloma to Light-Chain Amyloidosis","year":2025,"lang":"en","type":"review","venue":"Current Oncology","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; Occupational Cancer Research Centre; University of Calgary","funders":"","keywords":"Medicine; Plasma cell dyscrasia; Amyloidosis; AL amyloidosis; Multiple myeloma; Context (archaeology); Tolerability; Oncology; Plasma cell; Immunoglobulin light chain; Internal medicine; Immunology; Adverse effect; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003067536,0.0004720353,0.0008358159,0.001732132,0.0001970465,0.0007012876,0.0004800455,0.0007101382,0.004042629],"category_scores_gemma":[0.000495247,0.0001649327,0.0005700766,0.001481595,0.0002548773,0.0006742107,0.0004977522,0.001318755,0.001351502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003894536,"about_ca_system_score_gemma":0.0007348533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008345994,"about_ca_topic_score_gemma":0.001909406,"domain_scores_codex":[0.9998773,0.0000212755,0.0000199059,0.00002308121,0.00004571593,0.00001259898],"domain_scores_gemma":[0.9998363,0.00008469225,0.00002709078,0.000004261728,0.0000335261,0.00001411288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008461778,0.00005744361,0.0001092018,0.02137738,0.00009111999,0.000172784,0.00005221997,0.0002376022,0.001164919,0.00179386,0.02665107,0.9482077],"study_design_scores_gemma":[0.00004921973,0.000147116,0.000934323,0.008053359,0.0002060503,0.002006821,0.00004749835,0.00009087026,0.0005178831,0.001508698,0.9864252,0.00001292447],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001996983,0.9982257,0.00007571356,0.0002460812,0.0001640889,0.000005773676,0.00001944771,0.000006953956,0.001056501],"genre_scores_gemma":[0.001099121,0.9975,0.0001297612,0.000389853,0.0001294804,0.000007973429,0.00003982539,0.000001734254,0.0007023105],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004042629,"threshold_uncertainty_score":0.01352394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1093287644777303,"score_gpt":0.4290244507759555,"score_spread":0.3196956862982252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}