{"id":"W4412931261","doi":"10.1021/envhealth.5c00141","title":"Organoid for Air Pollution Toxicity Assessment: Advances and Environmental Applicability","year":2025,"lang":"en","type":"article","venue":"Environment & Health","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada","funders":"National Natural Science Foundation of China","keywords":"Organoid; Toxicity; Pollution; Chemical toxicity; Environmental science; Environmental pollution; Air pollution; Environmental chemistry; Environmental protection; Biology; Medicine; Chemistry; Ecology; Internal medicine; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002922919,0.0009826472,0.001318564,0.002405942,0.0005148744,0.00232161,0.0009350374,0.001531706,0.00245028],"category_scores_gemma":[0.002033419,0.0004226362,0.001454476,0.001737893,0.001176726,0.00184809,0.001568876,0.002142229,0.00100117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001139495,"about_ca_system_score_gemma":0.001441998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001471565,"about_ca_topic_score_gemma":0.002101012,"domain_scores_codex":[0.9981508,0.0005038375,0.0001590198,0.0004001545,0.0007005571,0.00008563092],"domain_scores_gemma":[0.9983013,0.0006188864,0.0002143886,0.0001756393,0.0006013612,0.0000884952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005132336,0.000227615,0.004332098,0.01627724,0.0003007571,0.001050605,0.0006561497,0.005370438,0.5691127,0.0167661,0.005990508,0.3794025],"study_design_scores_gemma":[0.00003049689,0.001351773,0.005638955,0.002536764,0.0006691706,0.0025241,0.0008620641,0.003103831,0.3863456,0.0120149,0.5847355,0.0001869302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.04648497,0.7546964,0.1655826,0.003035642,0.001244331,0.0005731598,0.002896321,0.0005181718,0.02496831],"genre_scores_gemma":[0.263645,0.6271407,0.09538909,0.001736514,0.0003814213,0.0006909355,0.002729111,0.0002282082,0.008059075],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002922919,"threshold_uncertainty_score":0.01545805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316830076052117,"score_gpt":0.3173305390980269,"score_spread":0.3041622383375057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}