{"id":"W4412938500","doi":"10.1172/jci195258","title":"Integrin α4β7 as a predictor of HIV acquisition: one thread in a complex tapestry","year":2025,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Human immunodeficiency virus (HIV); Thread (computing); Integrin; Computational biology; Medicine; Biology; Virology; Computer science; Internal medicine; Receptor; Programming language","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003041322,0.0003515235,0.0009459723,0.0007164208,0.001276789,0.001964388,0.0009562492,0.007440082,0.002089791],"category_scores_gemma":[0.01309324,0.0002485638,0.000421714,0.0005778086,0.001288655,0.002106389,0.0005885331,0.007753303,0.001733335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001077451,"about_ca_system_score_gemma":0.0009632055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002044303,"about_ca_topic_score_gemma":0.002530482,"domain_scores_codex":[0.9983902,0.0006657388,0.0002132807,0.0002579531,0.0003434482,0.0001293242],"domain_scores_gemma":[0.9906389,0.006080433,0.0004243003,0.0003844716,0.001830117,0.0006418215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000826807,0.0002415758,0.1087618,0.000426926,0.0001759301,0.01243065,0.0007103592,0.0002815534,0.00273669,0.006097051,0.6881903,0.1791202],"study_design_scores_gemma":[0.0007246,0.0009407941,0.1167949,0.003060702,0.0006729403,0.06166132,0.005694574,0.01100922,0.00384225,0.09068017,0.7045454,0.0003731664],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.009624692,0.01068878,0.0003879118,0.9651445,0.01140337,0.00001064707,0.00007953231,0.00003617597,0.002624504],"genre_scores_gemma":[0.166322,0.02108767,0.002381311,0.5830057,0.221056,0.00005692743,0.000165825,0.00005600222,0.005868677],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.007440082,"threshold_uncertainty_score":0.01608425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1101091707838885,"score_gpt":0.3868738004783365,"score_spread":0.276764629694448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}