{"id":"W4413001309","doi":"10.1016/j.bbcan.2025.189408","title":"Inhibition of nucleotide excision repair proteins associated with cancer chemotherapy","year":2025,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Nucleotide excision repair; Chemotherapy; DNA repair; Cancer research; Nucleotide; Cancer chemotherapy; Medicine; Chemistry; Biology; Gene; Genetics; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000582002,0.001138745,0.00288007,0.0002257965,0.0001083214,0.00004166332,0.0005871539,0.0007592067,0.00009979324],"category_scores_gemma":[0.000198682,0.0008329895,0.001614101,0.0008632768,0.0001774982,0.00001559019,0.0002165359,0.0005143901,0.00001727091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000303022,"about_ca_system_score_gemma":0.001165363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006792394,"about_ca_topic_score_gemma":0.00008360323,"domain_scores_codex":[0.9953789,0.0007075824,0.0013308,0.001528793,0.0005073309,0.0005465918],"domain_scores_gemma":[0.9959335,0.0000731719,0.002061247,0.001525228,0.0002546192,0.0001522479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004302829,0.00123417,7.206996e-7,0.03565513,0.002369832,0.000008270268,0.00008047051,0.000002387968,0.4246576,0.00009443839,0.02655227,0.5089144],"study_design_scores_gemma":[0.0006023683,0.0007410315,0.000008181046,0.0791522,0.0009870504,0.000001856595,0.00000333972,0.00000243586,0.2561089,0.00001462465,0.6615073,0.0008706673],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01350838,0.9793066,0.0000201267,0.0002058377,0.0003245581,0.005014366,0.001002544,0.0001145895,0.0005029801],"genre_scores_gemma":[0.000542952,0.9923146,0.0004229279,0.0008203804,0.0003881051,0.0027142,0.001035284,0.0001981024,0.001563435],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.634955,"threshold_uncertainty_score":0.9994121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02722082368675308,"score_gpt":0.3273629503718598,"score_spread":0.3001421266851066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}