{"id":"W4413007494","doi":"10.3390/curroncol32080441","title":"Efficacy and Safety of Dose-Dense Chemotherapy in Breast Cancer: Real Clinical Data and Literature Review","year":2025,"lang":"en","type":"review","venue":"Current Oncology","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Pegfilgrastim; Breast cancer; Docetaxel; Chemotherapy; Internal medicine; Oncology; Epirubicin; Adverse effect; Cyclophosphamide; Neutropenia; Leukocytopenia; Regimen; Febrile neutropenia; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001825324,0.0006818541,0.00249315,0.003832589,0.0002335218,0.001114769,0.001022403,0.000736717,0.00279484],"category_scores_gemma":[0.004647282,0.0003176169,0.001452789,0.005271078,0.0004764834,0.001135733,0.0005267381,0.0006332259,0.0004437894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007167551,"about_ca_system_score_gemma":0.002276411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174469,"about_ca_topic_score_gemma":0.002206636,"domain_scores_codex":[0.9991208,0.0001584963,0.0003586787,0.0001069698,0.0002252229,0.00002986938],"domain_scores_gemma":[0.9959862,0.002682089,0.0007299249,0.0000734855,0.000467327,0.00006093004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002842518,0.00006234163,0.00119028,0.3288358,0.001398848,0.000253207,0.0001497802,0.0002992959,0.0007211573,0.0007493256,0.008501642,0.6575541],"study_design_scores_gemma":[0.0002306725,0.0009540715,0.01923526,0.3653862,0.02119877,0.008706598,0.0006018453,0.000396214,0.001691383,0.001989393,0.5794886,0.0001210742],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002737169,0.9993256,0.00003534956,0.00006736049,0.0000280826,0.00000975794,0.00004412715,0.000002263741,0.000213819],"genre_scores_gemma":[0.001994349,0.9976506,0.0001063174,0.0001002038,0.00003495209,0.00001086396,0.0000573658,0.000001382491,0.00004403467],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003832589,"threshold_uncertainty_score":0.00965333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1759785187566098,"score_gpt":0.5474375033286019,"score_spread":0.371458984571992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}