{"id":"W4413008765","doi":"10.3390/vaccines13080835","title":"The Immunoproteasome Is Expressed but Dispensable for a Leukemia Infected Cell Vaccine","year":2025,"lang":"en","type":"article","venue":"Vaccines","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Institut Du Cancer de Montréal; Université de Montréal","keywords":"Oncolytic virus; Vesicular stomatitis virus; Leukemia; Biology; Virology; Cancer research; Virus; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001629843,0.0002249502,0.0002398684,0.0001084993,0.0001091017,0.0005291503,0.0001977623,0.0002751726,0.001803309],"category_scores_gemma":[0.0002043171,0.0001240037,0.0002037752,0.00009704709,0.0002178768,0.0003294026,0.0001988247,0.0006097052,0.0006622924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003211232,"about_ca_system_score_gemma":0.0002267407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001210938,"about_ca_topic_score_gemma":0.0001394082,"domain_scores_codex":[0.9998368,0.00002473679,0.00002110103,0.00003756592,0.00004858207,0.00003115819],"domain_scores_gemma":[0.9997422,0.00005007907,0.00009809692,0.00004744041,0.00002411155,0.00003808071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006218635,0.00001660625,0.0002144238,0.0000249929,0.000003206188,0.00003380171,0.00000598412,0.00005093647,0.998646,0.0001685733,0.0000245046,0.0007489079],"study_design_scores_gemma":[0.00001313682,0.0001406402,0.003128442,0.00001045833,0.00001450619,0.0004870086,0.00002087629,0.0008949813,0.9914717,0.00009538135,0.00371993,0.000002909312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874682,0.002092299,0.007004291,0.0001600389,0.00005240963,0.00003628108,0.0007351608,0.00008982274,0.002361486],"genre_scores_gemma":[0.995212,0.0003200473,0.002095845,0.00004941336,0.000007491901,0.0000188004,0.0008927855,0.00002250937,0.001381198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001803309,"threshold_uncertainty_score":0.006032646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009277139524828787,"score_gpt":0.2787863391496148,"score_spread":0.269509199624786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}