{"id":"W4413024574","doi":"10.1002/jev2.70137","title":"Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition","year":2025,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Montreal General Hospital","funders":"Vlaamse regering; New York University Abu Dhabi; Fonds Wetenschappelijk Onderzoek; Fonds De La Recherche Scientifique - FNRS; Ligue Contre le Cancer; KU Leuven","keywords":"PDZ domain; Cell biology; Biology; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002457048,0.000145341,0.0003464234,0.0003295636,0.0002384621,0.00001185857,0.0001444528,0.0001316739,0.00007046374],"category_scores_gemma":[0.00001620795,0.000113484,0.0002390109,0.0001816249,0.0001526208,0.0001358551,0.00002876874,0.0003865077,0.00001237953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004107719,"about_ca_system_score_gemma":0.0000397319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001907645,"about_ca_topic_score_gemma":0.000001804058,"domain_scores_codex":[0.9988368,0.0001384995,0.0006294942,0.0001191445,0.00005902933,0.0002170503],"domain_scores_gemma":[0.9992135,0.0001125175,0.0004292649,0.00009484818,0.0001271741,0.00002265988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002059307,0.0003040291,0.0003435016,0.00005094517,0.000243091,0.000007501382,0.0006999343,0.00002329476,0.9795632,0.0001686811,0.008948954,0.009440888],"study_design_scores_gemma":[0.0009201154,0.0002016375,0.0002006964,0.0003561136,0.0001533163,0.00007670068,0.001027816,0.00001068453,0.9367504,0.0001366753,0.06006594,0.00009998032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9407841,0.0530366,0.003690422,0.0007610323,0.00114323,0.0001000118,0.00001301595,0.00001581207,0.0004557725],"genre_scores_gemma":[0.9956232,0.0004754922,0.0002301657,0.00003561934,0.0000662508,0.000001537978,0.000009837371,0.000009185169,0.003548724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05483909,"threshold_uncertainty_score":0.4627745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006838794550818865,"score_gpt":0.2342354334101945,"score_spread":0.2273966388593756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}