{"id":"W4413024574","doi":"10.1002/jev2.70137","title":"Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition","year":2025,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Montreal General Hospital","funders":"Vlaamse regering; New York University Abu Dhabi; Fonds Wetenschappelijk Onderzoek; Fonds De La Recherche Scientifique - FNRS; Ligue Contre le Cancer; KU Leuven","keywords":"PDZ domain; Cell biology; Biology; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009392361,0.0003032595,0.0003390253,0.0001538228,0.0001484612,0.0002323184,0.0002358554,0.0001994317,0.001149096],"category_scores_gemma":[0.00009497021,0.0001025978,0.0001682929,0.0001045562,0.0002014116,0.0001752817,0.0001066875,0.0007253239,0.0002786214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002979167,"about_ca_system_score_gemma":0.0002744358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005290711,"about_ca_topic_score_gemma":0.001046055,"domain_scores_codex":[0.9999056,0.00001669429,0.000008863406,0.00001715901,0.00002237508,0.00002936693],"domain_scores_gemma":[0.9999517,0.000013711,0.000009081296,0.000005630934,0.000004003049,0.00001578274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006835716,0.0003599987,0.0001520275,0.00005253926,0.00002038129,0.00003724466,0.00002451958,0.0002137842,0.9944221,0.0002341971,0.0001644021,0.003635291],"study_design_scores_gemma":[0.0000723539,0.0007937409,0.001060079,0.000002954327,0.00001958656,0.0000687794,0.0000134882,0.001472008,0.9944224,0.00003808905,0.002032515,0.000004069819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966518,0.0009686886,0.0007656015,0.00007392175,0.00003434394,0.00003568914,0.0002097675,0.00007591488,0.001184302],"genre_scores_gemma":[0.995517,0.0009145623,0.001222064,0.00003967444,0.00001141959,0.00005636015,0.0004681379,0.00001782669,0.00175303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001149096,"threshold_uncertainty_score":0.003844082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006838794550818865,"score_gpt":0.2342354334101945,"score_spread":0.2273966388593756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}