{"id":"W4413027569","doi":"10.1016/j.modpat.2025.100846","title":"Human Papillomavirus–Associated Penile Squamous Cell Carcinoma With Acquired p16 Null Immunophenotype","year":2025,"lang":"en","type":"letter","venue":"Modern Pathology","topic":"Genital Health and Disease","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Immunophenotyping; Pathology; Human papillomavirus; Basal cell; Medicine; Null (SQL); Flow cytometry; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005538764,0.0005988317,0.0005427651,0.0006752061,0.00201487,0.001197792,0.0008724254,0.01136711,0.005993627],"category_scores_gemma":[0.005292779,0.0004249113,0.000658309,0.0004969941,0.001229022,0.001302207,0.0006569076,0.007314409,0.001136534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002003155,"about_ca_system_score_gemma":0.00148524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005559542,"about_ca_topic_score_gemma":0.006521133,"domain_scores_codex":[0.9993836,0.0001319063,0.00006094804,0.00009250492,0.0001406598,0.0001903354],"domain_scores_gemma":[0.998912,0.0005013916,0.00008772585,0.00006854135,0.000144972,0.0002853878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001589295,0.00009796483,0.01130969,0.00007077924,0.00002504956,0.8995129,0.0003049338,0.0001833414,0.001313268,0.003357508,0.07668353,0.006982049],"study_design_scores_gemma":[0.0001424598,0.0002897612,0.01915113,0.0002324658,0.00007368577,0.8519737,0.001161358,0.002605636,0.001260414,0.00658972,0.1164583,0.00006133247],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1704803,0.004754862,0.001264409,0.6595897,0.03412348,0.0002247821,0.0006380241,0.0001387368,0.1287857],"genre_scores_gemma":[0.7215496,0.003792814,0.001337334,0.1802107,0.03872897,0.0000926342,0.000266343,0.00008014851,0.05394148],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01136711,"threshold_uncertainty_score":0.0200507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01583163090068753,"score_gpt":0.2605759345794124,"score_spread":0.2447443036787248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}