{"id":"W4413028394","doi":"10.26434/chemrxiv-2025-k1hs8","title":"Function from complexity: chemical systems that achieve sensing using host-type molecules and complex equilibria","year":2025,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Advanced Chemical Sensor Technologies","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Host (biology); Function (biology); Type (biology); Molecule; Computer science; Distributed computing; Nanotechnology; Chemistry; Materials science; Biology; Evolutionary biology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00003789992,0.0005676721,0.0007625688,0.0001180495,0.00006412383,0.0001381693,0.0003104101,0.0008033663,0.00001108079],"category_scores_gemma":[0.00009052585,0.0006316789,0.0001067372,0.0001859506,0.00028692,0.00008045023,0.0009481263,0.001007051,0.000005725629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037041,"about_ca_system_score_gemma":0.0000135536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096046,"about_ca_topic_score_gemma":0.000002527135,"domain_scores_codex":[0.9982353,0.0000229719,0.0003873796,0.0006968791,0.0002201924,0.0004372347],"domain_scores_gemma":[0.9988276,0.0001524699,0.0001257122,0.0007189254,0.00007796248,0.00009732109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003439615,0.000009158162,0.00007855633,0.000568923,0.0001942931,0.000009812138,0.00003487149,0.008939294,0.9891316,0.0001316545,0.0002468883,0.00062055],"study_design_scores_gemma":[0.0002750796,0.00000878534,0.0001235334,0.0006751155,0.0001683751,0.00001152382,0.0001458481,0.4292671,0.5599777,0.00768318,0.0009428355,0.000720876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9663181,0.00289628,0.02605517,0.00006117413,0.00122478,0.0003587951,0.00004276987,0.002093355,0.0009496202],"genre_scores_gemma":[0.9806437,0.0001705102,0.01851617,0.00003194645,0.0002219958,0.0000058837,0.0002992264,0.0000812993,0.00002924842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4291539,"threshold_uncertainty_score":0.9996135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07383627347820589,"score_gpt":0.2658843035446415,"score_spread":0.1920480300664356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}