{"id":"W4413055521","doi":"10.1038/s41564-025-02080-x","title":"Streptomyces uses both polar and dispersed cell wall synthesis during exploratory growth","year":2025,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Government of Canada; Natural Sciences and Engineering Research Council of Canada; Duquesne University; McMaster University; Université de Montréal; Harvard University","keywords":"Peptidoglycan; MreB; FtsZ; Cell envelope; Cell wall; Bacterial cell structure; Lipid II; Biology; Streptomyces albus; Cell division; Teichoic acid; Cell biology; Bacteria; Cell growth; Streptomyces; Biochemistry; Biophysics; Cell; Cytoskeleton; Escherichia coli; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007648282,0.0003054505,0.0001744151,0.0001808578,0.0001881507,0.0003699615,0.0001307543,0.0001588007,0.0003542063],"category_scores_gemma":[0.0001330136,0.0001408809,0.0001451653,0.0001233007,0.0002023147,0.0002555338,0.0003741949,0.0002515532,0.0002095935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001761067,"about_ca_system_score_gemma":0.0001445153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006160834,"about_ca_topic_score_gemma":0.001098966,"domain_scores_codex":[0.9998972,0.00001140799,0.000006896762,0.00003110579,0.00002650555,0.00002681648],"domain_scores_gemma":[0.9998307,0.00002335109,0.00005540678,0.00002104166,0.00001786254,0.00005158799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002512298,0.000004087769,0.0009276787,0.000007062244,8.446456e-7,0.00004533505,0.00001428352,0.00002099104,0.9982579,0.00003343091,0.000002492644,0.0006608188],"study_design_scores_gemma":[0.000004453866,0.0001775133,0.05996928,0.000006677832,0.000007489501,0.0007781651,0.0001669939,0.0005697033,0.9374579,0.00009407813,0.0007588069,0.000008906565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973111,0.000136975,0.001836045,0.00001360536,0.000002188962,0.000003716441,0.00006234617,0.0000299185,0.0006041842],"genre_scores_gemma":[0.997764,0.00008819093,0.001566342,0.000008902017,0.000001556302,0.00000436135,0.0001779463,0.00001043169,0.000378228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006160834,"threshold_uncertainty_score":0.001277685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002677470402648866,"score_gpt":0.1945415298084187,"score_spread":0.1918640594057698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}