{"id":"W4413055521","doi":"10.1038/s41564-025-02080-x","title":"Streptomyces uses both polar and dispersed cell wall synthesis during exploratory growth","year":2025,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Government of Canada; Natural Sciences and Engineering Research Council of Canada; Duquesne University; McMaster University; Université de Montréal; Harvard University","keywords":"Peptidoglycan; MreB; FtsZ; Cell envelope; Cell wall; Bacterial cell structure; Lipid II; Biology; Streptomyces albus; Cell division; Teichoic acid; Cell biology; Bacteria; Cell growth; Streptomyces; Biochemistry; Biophysics; Cell; Cytoskeleton; Escherichia coli; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007696314,0.0002037954,0.000220536,0.00007170064,0.0001405577,0.00001626739,0.0001780727,0.0004360083,0.000008417024],"category_scores_gemma":[0.00006366341,0.0001801829,0.00007192986,0.00006881518,0.000150744,9.788145e-7,0.0002219715,0.0001852128,0.000003000694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001304456,"about_ca_system_score_gemma":0.0000470197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000191764,"about_ca_topic_score_gemma":0.00007453116,"domain_scores_codex":[0.9990354,0.00007466879,0.0001557207,0.0004498954,0.00002049569,0.0002638765],"domain_scores_gemma":[0.9995766,0.00003972087,0.00005619176,0.0002294854,0.00005897246,0.00003907651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005473089,0.00003101053,0.0264759,0.00006224884,0.0001119115,0.000002292117,0.00005465314,8.752457e-7,0.9713577,0.00008977222,0.001671794,0.00008710992],"study_design_scores_gemma":[0.0004304853,0.00006259596,0.01972771,0.0000178005,0.00004893905,0.00001159431,0.0001897466,6.328116e-7,0.9449216,0.0000625475,0.03430222,0.0002241296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746086,0.02394423,0.000009324714,0.0003039258,0.0002328876,0.0001214602,0.0001155602,0.000007711681,0.0006563147],"genre_scores_gemma":[0.9965238,0.002000016,0.0003006203,0.0006375301,0.00008584507,0.00001905129,0.00004020221,0.00001577608,0.0003771594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03263043,"threshold_uncertainty_score":0.7347648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002677470402648866,"score_gpt":0.1945415298084187,"score_spread":0.1918640594057698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}