{"id":"W4413100294","doi":"10.1007/s40121-025-01208-0","title":"Safety and Efficacy of Fecal Microbiota, Live-jslm to Prevent Recurrent Clostridioides difficile Infection in Participants With Irritable Bowel Syndrome","year":2025,"lang":"en","type":"article","venue":"Infectious Diseases and Therapy","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Clostridioides; Irritable bowel syndrome; Medicine; Feces; Fecal bacteriotherapy; Internal medicine; Gastroenterology; Clostridium difficile; Intensive care medicine; Microbiology; Antibiotics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001403535,0.0003479241,0.0006654873,0.0002452306,0.0003416637,0.0004825065,0.0002523147,0.0004917207,0.002205472],"category_scores_gemma":[0.001413132,0.0001923467,0.001016122,0.000184533,0.0002171424,0.0003282596,0.0002596519,0.0005439998,0.0002428417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000349071,"about_ca_system_score_gemma":0.0006403316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008721424,"about_ca_topic_score_gemma":0.0028081,"domain_scores_codex":[0.9995323,0.0001913612,0.00005094625,0.00008875063,0.00008207449,0.00005453083],"domain_scores_gemma":[0.9992784,0.0001208216,0.000312974,0.00006233578,0.00009492834,0.00013058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5606247,0.01373011,0.1262132,0.003931134,0.005156748,0.0002407718,0.0005542905,0.0006300026,0.04055165,0.0001535658,0.001935182,0.2462786],"study_design_scores_gemma":[0.07431658,0.5002814,0.3988007,0.0005771471,0.006190719,0.0007402928,0.0005862007,0.001261806,0.01189942,0.0002266301,0.005044922,0.00007427283],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966804,0.002062512,0.0001390785,0.00008054829,0.0000289093,0.0001936829,0.0003360231,0.00001944037,0.0004592777],"genre_scores_gemma":[0.9984805,0.0004049051,0.0003301296,0.0001117105,0.00002239706,0.0001325677,0.0002082818,0.000003226692,0.000306382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002205472,"threshold_uncertainty_score":0.007422745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01408009849319838,"score_gpt":0.2968972164736546,"score_spread":0.2828171179804563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}