{"id":"W4413104600","doi":"10.1093/cid/ciaf438","title":"Long-term Immunogenicity and Boostability of the 13-valent Pneumococcal Conjugate Vaccine Followed by the 23-valent Pneumococcal Polysaccharide Vaccine in Adults Receiving Immunosuppressive Therapy and Adults With HIV—3-year Follow-up of a Prospective Cohort Study","year":2025,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"ZonMw","keywords":"Medicine; Immunogenicity; Pneumococcal polysaccharide vaccine; Pneumococcal conjugate vaccine; Pneumococcal vaccine; Immunology; Human immunodeficiency virus (HIV); Streptococcus pneumoniae; Virology; Immune system; Pneumococcal disease; Microbiology; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001386166,0.0004875438,0.0004953832,0.000605021,0.0007056934,0.000874784,0.0004719511,0.000718924,0.0007156832],"category_scores_gemma":[0.002180862,0.0004690367,0.001108503,0.000644218,0.0002876911,0.0006625433,0.0005272811,0.001034588,0.0002997144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004056818,"about_ca_system_score_gemma":0.0004141848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007793475,"about_ca_topic_score_gemma":0.004715358,"domain_scores_codex":[0.9994482,0.0001133212,0.00006013603,0.0001444802,0.0001067025,0.000127011],"domain_scores_gemma":[0.9984038,0.0001588888,0.0006254613,0.0001895082,0.0002307682,0.0003914904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003601584,0.00008551065,0.9984861,0.000004796203,0.00008950933,0.00006836918,0.00008227699,0.00002019109,0.000256001,0.000003963868,0.00003623553,0.0005069978],"study_design_scores_gemma":[0.00001434196,0.0004556885,0.9989665,0.000003590262,0.00004843537,0.000184641,0.0001027392,0.00006757487,0.00007203776,0.000004821883,0.00007598154,0.000003624901],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995303,0.0001025888,0.00002985177,0.00001089171,0.000004274664,0.000009657701,0.0002146879,0.000001521241,0.00009632355],"genre_scores_gemma":[0.9993862,0.00006495845,0.00003912943,0.00001880525,0.000006684061,0.00001069833,0.000366226,0.000001359113,0.0001059862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007793475,"threshold_uncertainty_score":0.01549625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00972598039795133,"score_gpt":0.2939091995257728,"score_spread":0.2841832191278215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}