{"id":"W4413105795","doi":"10.1093/noajnl/vdaf123.110","title":"RMTD-04 THE INCIDENCE OF BRAIN METASTASES (BRM) AS A FIRST SITE OF METASTATIC RECURRENCE AMONG PATIENTS WITH EARLY-STAGE BREAST CANCER (BC): A SYSTEMATIC REVIEW AND META-ANALYSIS","year":2025,"lang":"en","type":"review","venue":"Neuro-Oncology Advances","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto; McMaster University","funders":"","keywords":"Medicine; Incidence (geometry); Meta-analysis; Internal medicine; Cumulative incidence; Oncology; Breast cancer; Metastatic breast cancer; Cochrane Library; Subgroup analysis; Stage (stratigraphy); Cancer; Randomized controlled trial; Cohort; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01333452,0.00208096,0.01406263,0.00752576,0.0006129511,0.003563232,0.001873757,0.002145414,0.0045735],"category_scores_gemma":[0.03313294,0.001229047,0.0354913,0.008049337,0.0006635895,0.001700857,0.001482753,0.001884245,0.0004515055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00292292,"about_ca_system_score_gemma":0.003164527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006257996,"about_ca_topic_score_gemma":0.01510573,"domain_scores_codex":[0.98975,0.005237464,0.002640676,0.0009627531,0.001143295,0.0002658456],"domain_scores_gemma":[0.9791086,0.01516887,0.003191077,0.0005950865,0.001645393,0.0002909156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002399649,0.00002691068,0.005102855,0.4660771,0.5127765,0.0001402996,0.00008783423,0.0005498133,0.0001956923,0.0001355604,0.001043208,0.01146455],"study_design_scores_gemma":[0.0009252777,0.0002420035,0.005567721,0.03497459,0.9555898,0.000161671,0.00004619061,0.0002145873,0.0001140155,0.0001542974,0.001983856,0.00002595602],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006727943,0.9908918,0.0003942955,0.0002034683,0.0001371716,0.000318702,0.0009206849,0.0000248189,0.0003811757],"genre_scores_gemma":[0.1990939,0.7934124,0.00236215,0.001003452,0.0003050612,0.001658978,0.001465127,0.00004118846,0.0006577449],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01406263,"threshold_uncertainty_score":0.07052046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03389536534619973,"score_gpt":0.3626249066175778,"score_spread":0.3287295412713781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}