{"id":"W4413105795","doi":"10.1093/noajnl/vdaf123.110","title":"RMTD-04 THE INCIDENCE OF BRAIN METASTASES (BRM) AS A FIRST SITE OF METASTATIC RECURRENCE AMONG PATIENTS WITH EARLY-STAGE BREAST CANCER (BC): A SYSTEMATIC REVIEW AND META-ANALYSIS","year":2025,"lang":"en","type":"review","venue":"Neuro-Oncology Advances","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto; McMaster University","funders":"","keywords":"Medicine; Incidence (geometry); Meta-analysis; Internal medicine; Cumulative incidence; Oncology; Breast cancer; Metastatic breast cancer; Cochrane Library; Subgroup analysis; Stage (stratigraphy); Cancer; Randomized controlled trial; Cohort; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001253152,0.0008978995,0.01305203,0.0004909221,0.0001468165,0.00002101682,0.0004365047,0.0001397141,0.0003524353],"category_scores_gemma":[0.001484635,0.0004300767,0.001991346,0.002287858,0.0007811881,0.0002364819,0.0002169043,0.0005539166,0.000004911998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001164329,"about_ca_system_score_gemma":0.0006719923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008855405,"about_ca_topic_score_gemma":0.001748421,"domain_scores_codex":[0.9932235,0.002467948,0.002113708,0.0009828276,0.0008002977,0.0004117551],"domain_scores_gemma":[0.9876859,0.006624534,0.003667711,0.001271908,0.0005722104,0.0001778004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00008849421,0.0005053642,0.001426823,0.8706157,0.1180025,0.0001388734,0.00009736946,0.00001724683,6.834589e-8,0.00008051802,0.0001054968,0.008921557],"study_design_scores_gemma":[0.0006449137,0.001041225,0.0004370306,0.06008111,0.9140836,0.00009330292,0.00003627421,0.000002476906,0.000001468442,0.00001007018,0.02327078,0.0002977289],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000153613,0.987544,0.00005632688,0.0006667087,0.00006136704,0.007447635,0.00400555,0.00001998777,0.00004478502],"genre_scores_gemma":[0.0007661846,0.9945327,0.0005865595,0.0008397322,0.000009043256,0.002824969,0.0001847828,0.00003726113,0.0002187704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8105346,"threshold_uncertainty_score":0.9998151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03389536534619973,"score_gpt":0.3626249066175778,"score_spread":0.3287295412713781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}