{"id":"W4413105938","doi":"10.1093/noajnl/vdaf123.137","title":"TRLS-14 CLINICOPATHOLOGIC CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH KRAS G12C MUTANT NSCLC WITH BRAIN METASTASES","year":2025,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Medicine; KRAS; Internal medicine; Oncology; Cohort; STK11; Population; Retrospective cohort study; Cancer; Lung cancer; Gastroenterology; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008611217,0.0001899866,0.0006289179,0.0001123105,0.00008512632,0.000006803147,0.00005810085,0.00006199634,0.00002345678],"category_scores_gemma":[0.000302772,0.00010917,0.00004017566,0.0001510766,0.0003310011,0.0001080364,0.00003152831,0.0001407559,0.000001666386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004371328,"about_ca_system_score_gemma":0.0002274356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005004471,"about_ca_topic_score_gemma":0.0000456176,"domain_scores_codex":[0.9989488,0.00009361809,0.000314117,0.0003206427,0.0001364474,0.000186432],"domain_scores_gemma":[0.9985913,0.0007346201,0.0002419458,0.0002063359,0.0001592732,0.00006651675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001167331,0.0006513235,0.9594445,0.00008621376,0.0002165822,0.0001340076,0.0001542394,0.000004057083,0.0004293787,0.0002284923,0.00009264051,0.0373912],"study_design_scores_gemma":[0.006575231,0.004557324,0.9589548,0.00007742988,0.0009131267,0.00002380188,0.0001547708,0.000003766588,0.0006284613,0.00009609726,0.02790658,0.0001085729],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945146,0.0005183254,0.0002445814,0.002318381,0.0002549741,0.0006711209,0.0001658775,0.00004173268,0.001270413],"genre_scores_gemma":[0.9941671,0.0002348731,0.002204538,0.002999739,0.00001748271,0.00007748893,0.00007427347,0.00001406742,0.0002103617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03728263,"threshold_uncertainty_score":0.4451824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0099296812370401,"score_gpt":0.3400719256120922,"score_spread":0.3301422443750521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}