{"id":"W4413105938","doi":"10.1093/noajnl/vdaf123.137","title":"TRLS-14 CLINICOPATHOLOGIC CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH KRAS G12C MUTANT NSCLC WITH BRAIN METASTASES","year":2025,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Medicine; KRAS; Internal medicine; Oncology; Cohort; STK11; Population; Retrospective cohort study; Cancer; Lung cancer; Gastroenterology; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002883476,0.0001314449,0.000221875,0.0005727804,0.0002470865,0.0003870849,0.0002221906,0.0002410314,0.001885372],"category_scores_gemma":[0.000697914,0.0001163763,0.0003085045,0.0005196473,0.0001866704,0.0002860754,0.0002801434,0.0002367433,0.0003271892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002991485,"about_ca_system_score_gemma":0.0002685689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001942857,"about_ca_topic_score_gemma":0.003109667,"domain_scores_codex":[0.999813,0.0000277275,0.0000292024,0.00005607586,0.00003478557,0.00003917583],"domain_scores_gemma":[0.9993424,0.00007061988,0.0002978441,0.00002742533,0.00007573568,0.0001859759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001310441,0.00001251735,0.99839,0.00000384501,0.00001846166,0.0001251109,0.00001078671,0.00004511882,0.0003181433,0.000006132764,0.00007887698,0.0008600028],"study_design_scores_gemma":[0.000007849253,0.000167666,0.9980807,0.000003070645,0.00001976148,0.001165334,0.00007172921,0.0001762192,0.0001296054,0.00001463287,0.0001606797,0.000002807262],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992517,0.00009605008,0.00003320526,0.0000139698,0.000002498973,0.000003396021,0.0003082764,0.000002790871,0.0002880575],"genre_scores_gemma":[0.9994773,0.00002166544,0.00001781627,0.000005280607,0.000004537279,0.00000365214,0.0003716418,8.173294e-7,0.00009720218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001942857,"threshold_uncertainty_score":0.006307244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0099296812370401,"score_gpt":0.3400719256120922,"score_spread":0.3301422443750521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}