{"id":"W4413108210","doi":"10.1002/ame2.70063","title":"Development, validation, and preliminary phenotypic characterization of a <i>Col6a3</i> knockout mouse model targeting exon 3","year":2025,"lang":"en","type":"article","venue":"Animal Models and Experimental Medicine","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Université de Sherbrooke","keywords":"Phenotype; Knockout mouse; Exon; Myopathy; Chemistry; Collagen VI; Cancer research; Gene; Molecular biology; Pathology; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766557,0.0001678687,0.0003282579,0.0001816819,0.000115488,0.00001031723,0.00005539079,0.00007607239,0.00003516431],"category_scores_gemma":[0.00003450583,0.000140861,0.00002115452,0.0001548554,0.0001589768,0.0001461424,0.0001548202,0.0001133596,0.000001115853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004868131,"about_ca_system_score_gemma":0.00008889651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002420717,"about_ca_topic_score_gemma":3.803131e-7,"domain_scores_codex":[0.998767,0.00002564722,0.0004032986,0.000322946,0.0002828836,0.0001982325],"domain_scores_gemma":[0.9995248,0.00002632799,0.00008098978,0.0001285388,0.0001051353,0.000134244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001055758,0.0001617714,0.0003428536,0.0002206492,0.00003206377,0.000002790441,0.002270654,0.00002442164,0.9933218,0.0008080972,0.0001238321,0.001635267],"study_design_scores_gemma":[0.002082824,0.0006911609,0.001086193,0.000305494,0.00003894255,0.000007246656,0.0009233797,0.0820623,0.9124522,0.00009004358,0.00014465,0.0001155264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912435,0.001482237,0.00497047,0.0004729253,0.00002291484,0.0004729374,0.000003375357,0.00003041502,0.001301206],"genre_scores_gemma":[0.9945307,0.0002521293,0.003504225,0.000350473,0.00003853575,0.00004815191,0.00009660942,0.00001971787,0.001159395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08203787,"threshold_uncertainty_score":0.5744143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03198606776316343,"score_gpt":0.3129999511247973,"score_spread":0.2810138833616339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}