{"id":"W4413108990","doi":"10.1002/advs.202504562","title":"Polyadenylation Complex CFII Recognizes Downstream Cis‐element for Pre‐mRNA Polyadenylation Through Interaction with an RNA‐Binding Protein in Arabidopsis","year":2025,"lang":"en","type":"article","venue":"Advanced Science","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Natural Science Foundation of China; Capital Normal University; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; National Science Foundation","keywords":"Polyadenylation; RNA; Messenger RNA; RNA-binding protein; Cleavage and polyadenylation specificity factor; Biology; Arabidopsis; Proteome; Cell biology; Three prime untranslated region; Binding site; Genetics; Untranslated region; Mutant; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008677666,0.0003035901,0.0002349198,0.0002441474,0.0003189703,0.0003506856,0.0002212159,0.0003260314,0.0008575603],"category_scores_gemma":[0.00010559,0.0002081112,0.0002484891,0.0001499862,0.0001535504,0.0001931693,0.0001801635,0.0005272336,0.0005106946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008975095,"about_ca_system_score_gemma":0.0001817765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002861975,"about_ca_topic_score_gemma":0.002873792,"domain_scores_codex":[0.9998437,0.00001005004,0.000006593664,0.00005896866,0.00005088369,0.00002974483],"domain_scores_gemma":[0.999933,0.000007298295,0.00001548439,0.00000604192,0.000008303892,0.00002980695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001984394,0.000003591597,0.000148,0.00001048309,0.000001755659,0.00003398531,0.000006498135,0.00001944543,0.99925,0.00006700589,0.00003481326,0.0004045544],"study_design_scores_gemma":[0.00001244322,0.00004864949,0.03319877,0.00001309323,0.00001783564,0.0007636134,0.00004503678,0.00281967,0.9579532,0.0001666879,0.004947552,0.00001358024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848167,0.003040504,0.008037321,0.0002161302,0.00006589889,0.00002018745,0.0005211685,0.0002413734,0.003040611],"genre_scores_gemma":[0.9900898,0.0004629532,0.00487474,0.0001197739,0.00001090982,0.00001602404,0.0008499115,0.00002999712,0.003545916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002861975,"threshold_uncertainty_score":0.006511927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02415692088249532,"score_gpt":0.3558348632781344,"score_spread":0.331677942395639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}