{"id":"W4413112761","doi":"10.1098/rsob.240202","title":"Selective loss of ATP carriers in favour of SLC25A43 orthologues in metamonad mitochondria adapted to anaerobiosis","year":2025,"lang":"en","type":"article","venue":"Open Biology","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"European Research Council; Grantová Agentura České Republiky; Ministerstvo Školství, Mládeže a Tělovýchovy; Grantová Agentura, Univerzita Karlova; Gordon and Betty Moore Foundation","keywords":"Biology; Mitochondrion; Oxidative phosphorylation; Chemiosmosis; Cytosol; ATP synthase; ATP–ADP translocase; Bioenergetics; Mitochondrial carrier; Cell biology; Adenosine triphosphate; Phosphorylation; Biochemistry; Substrate-level phosphorylation; Uncoupling Agents; Inner mitochondrial membrane; Anaerobic exercise; Bacterial outer membrane; Gene; Enzyme; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009281229,0.0002051725,0.0002347414,0.0006473418,0.0004131698,0.0004332817,0.0001668693,0.000462384,0.0007369561],"category_scores_gemma":[0.0002484295,0.0001172677,0.0002069078,0.0003531186,0.0003164927,0.0002900889,0.0005050997,0.0003677364,0.0002742397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001723739,"about_ca_system_score_gemma":0.0001186316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006237262,"about_ca_topic_score_gemma":0.0009630389,"domain_scores_codex":[0.9999076,0.000008669018,0.000009213349,0.00003623187,0.00001849138,0.00001986562],"domain_scores_gemma":[0.9998354,0.0000226117,0.00005559547,0.00001649367,0.00001773358,0.00005218848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001786768,0.0000109821,0.0112161,0.00004749283,0.00001214235,0.0003583922,0.0002271182,0.00007193397,0.9854382,0.0001218744,0.00004160908,0.002275551],"study_design_scores_gemma":[0.00002812029,0.0004232544,0.8631744,0.00007523816,0.00008715585,0.005530459,0.001401142,0.002497938,0.1139583,0.000644962,0.01211607,0.00006299694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985695,0.0002494378,0.0004697539,0.00002884917,0.000006454652,0.000003509822,0.0002657182,0.00001851773,0.0003883352],"genre_scores_gemma":[0.997959,0.0001280785,0.0008664209,0.00005202828,0.000003999006,0.000006949751,0.0004946954,0.00001031605,0.0004784534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007369561,"threshold_uncertainty_score":0.002465367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246365211319379,"score_gpt":0.287893452371381,"score_spread":0.2754298002581873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}