{"id":"W4413113302","doi":"10.1111/pim.70018","title":"<i>Schistosoma japonicum</i> ‐Derived Peptide <scp>SJMHE1</scp> Attenuates Osteoarthritis by Promoting Synovial <scp>M2</scp> Macrophage Polarisation","year":2025,"lang":"en","type":"article","venue":"Parasite Immunology","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Magna International (Canada)","funders":"National Natural Science Foundation of China","keywords":"Schistosoma japonicum; Osteoarthritis; Macrophage; Peptide; Biology; Immunology; Schistosomiasis; Medicine; Pathology; Helminths; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004787797,0.0007030838,0.0009439323,0.0004977636,0.001183541,0.0001412455,0.0007585863,0.001084058,0.0001900733],"category_scores_gemma":[0.001994698,0.0007627084,0.0003791722,0.0005768971,0.0007084298,0.000446989,0.0003471309,0.001614552,0.003712119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002822483,"about_ca_system_score_gemma":0.0002246821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007716549,"about_ca_topic_score_gemma":0.0001952549,"domain_scores_codex":[0.9952571,0.0009789718,0.00112005,0.001080056,0.0001018201,0.001461986],"domain_scores_gemma":[0.9957262,0.002473675,0.0006163814,0.0008324425,0.0002708637,0.00008048332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005044311,0.0003794708,0.01630973,0.00003368103,0.0007520373,0.00003502607,0.001570105,0.000004069928,0.9489633,0.0006766994,0.02406901,0.007156454],"study_design_scores_gemma":[0.003402078,0.000649189,0.04076449,0.0001874024,0.0002594616,0.000587218,0.001385283,0.00002558684,0.5665372,0.0003114677,0.3856865,0.0002040991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9505218,0.03023523,0.0009149119,0.0005533799,0.003166055,0.0008284182,0.0004989923,0.0004376603,0.01284356],"genre_scores_gemma":[0.9632494,0.0007134096,0.0002029422,0.0008809854,0.0001040767,0.0002509393,0.001756951,0.00007934453,0.03276192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3824261,"threshold_uncertainty_score":0.9994824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005304806243649892,"score_gpt":0.2451758804966694,"score_spread":0.2398710742530195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}