{"id":"W4413116541","doi":"10.1126/scitranslmed.adu4643","title":"Proviruses in CD4 <sup>+</sup> T cells reactive to autologous antigens contribute to nonsuppressible HIV-1 viremia","year":2025,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; Clinique Paro Excellence","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Viremia; Virology; Antigen; Human immunodeficiency virus (HIV); Immunology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000219166,0.0002457,0.0001506439,0.0001861157,0.0001884042,0.0003880208,0.0001350569,0.0002834193,0.002370087],"category_scores_gemma":[0.0003139913,0.0001380722,0.0001529857,0.000070907,0.0002778396,0.0001598872,0.0002445327,0.0004484966,0.0004478069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001385128,"about_ca_system_score_gemma":0.0001210046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001331393,"about_ca_topic_score_gemma":0.0001640768,"domain_scores_codex":[0.9998453,0.00003223108,0.00001439727,0.00003440244,0.00003361618,0.00003999161],"domain_scores_gemma":[0.9998441,0.00004267327,0.00003662936,0.00002610184,0.00001988921,0.00003061771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003571216,0.0001996466,0.02356135,0.0001142563,0.00001778479,0.0008928084,0.000209914,0.0001005917,0.9529583,0.0003070989,0.0001541705,0.02112695],"study_design_scores_gemma":[0.0001752994,0.004896432,0.2212979,0.00007528417,0.0001602824,0.0183982,0.0007151733,0.003697212,0.7416043,0.001352008,0.007609152,0.00001873346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976641,0.000383689,0.0007095151,0.00005112474,0.00001508271,0.00002909954,0.00002771448,0.00003004508,0.001089693],"genre_scores_gemma":[0.998341,0.000153445,0.000468381,0.0000391208,0.00002266497,0.00001514869,0.00005818756,0.000005292133,0.0008968001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002370087,"threshold_uncertainty_score":0.007928729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630184770138362,"score_gpt":0.3163693362111041,"score_spread":0.3000674885097205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}