{"id":"W4413116541","doi":"10.1126/scitranslmed.adu4643","title":"Proviruses in CD4 <sup>+</sup> T cells reactive to autologous antigens contribute to nonsuppressible HIV-1 viremia","year":2025,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; Clinique Paro Excellence","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Viremia; Virology; Antigen; Human immunodeficiency virus (HIV); Immunology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000690105,0.0001571778,0.000292271,0.0007385905,0.0002723755,0.00001320057,0.0003673587,0.00007544374,0.0003965657],"category_scores_gemma":[0.0003564219,0.0001178738,0.00003084367,0.001413186,0.0007729178,0.0001404974,0.00004732743,0.0002260068,0.001020949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222195,"about_ca_system_score_gemma":0.0007347019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003307118,"about_ca_topic_score_gemma":0.0001532392,"domain_scores_codex":[0.998311,0.00009936278,0.0002951841,0.0005049275,0.0001892149,0.0006003545],"domain_scores_gemma":[0.9990681,0.0003747007,0.00002896338,0.0002330077,0.000180035,0.0001152266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006001885,0.0002251987,0.02452067,0.00001864756,0.00006520466,0.00004122649,0.003569868,0.001187308,0.9476057,0.001874383,0.008075727,0.01221593],"study_design_scores_gemma":[0.008543876,0.001163917,0.2862333,0.0007135148,0.00006964651,0.00003246202,0.001097728,0.00027834,0.5896533,0.00116543,0.1105974,0.0004510995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9431838,0.001093152,0.005215501,0.03758061,0.0004693573,0.001876296,0.0005118859,0.000081686,0.009987686],"genre_scores_gemma":[0.9963898,0.00001457637,0.000678583,0.0008108743,0.00002137474,0.00009214602,0.00008882255,0.000004998875,0.001898819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3579524,"threshold_uncertainty_score":0.9997569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630184770138362,"score_gpt":0.3163693362111041,"score_spread":0.3000674885097205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}