{"id":"W4413117040","doi":"10.1016/j.mbs.2025.109515","title":"Modeling and dynamics of Brucella infection-induced macrophage apoptosis inhibition","year":2025,"lang":"en","type":"article","venue":"Mathematical Biosciences","topic":"Brucella: diagnosis, epidemiology, treatment","field":"Veterinary","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"National Natural Science Foundation of China; Natural Science Foundation of Shandong Province; China Scholarship Council; York University; Natural Science Foundation of Jilin Province","keywords":"Brucella; Brucellosis; Virulence; Immune system; Biology; Macrophage; Chronic infection; Evasion (ethics); Microbiology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004768412,0.0005097115,0.0007257329,0.0005276237,0.0004140242,0.001003717,0.0009478218,0.001574195,0.002314441],"category_scores_gemma":[0.001868986,0.0003401288,0.0007807963,0.0003225352,0.0008138915,0.0008613954,0.0007310904,0.0009806952,0.0002398012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001547109,"about_ca_system_score_gemma":0.001477536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01959977,"about_ca_topic_score_gemma":0.009184121,"domain_scores_codex":[0.9998322,0.00005121947,0.000005997453,0.00002658679,0.00002995582,0.00005414004],"domain_scores_gemma":[0.9992869,0.0003581183,0.0001613117,0.00001963405,0.0001163466,0.00005770283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00003227398,0.0000363561,0.001074407,0.00003340486,0.00001565262,0.00006229017,0.00003604494,0.9710618,0.001649988,0.0243464,0.0004056855,0.001245632],"study_design_scores_gemma":[0.000003982645,0.00000873206,0.0001737972,0.000002695235,0.000004717085,0.000009936726,0.000008942069,0.9974445,0.0001129591,0.002084815,0.0001419038,0.000003058327],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6856156,0.002917898,0.2583666,0.004814661,0.000279504,0.0001051454,0.0008085257,0.0001980291,0.04689412],"genre_scores_gemma":[0.983164,0.0006264654,0.003873962,0.0001216745,0.00003522465,0.00007079438,0.0001086519,0.00002070444,0.01197839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01959977,"threshold_uncertainty_score":0.03897136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05958112332240509,"score_gpt":0.3492318553761722,"score_spread":0.2896507320537671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}