{"id":"W4413148372","doi":"10.18295/2075-0528.1377","title":"Immunotherapy for B-Cell Neoplasms using T Cells expressing Chimeric Antigen Receptors : From antigen choice to clinical implementation","year":2012,"lang":"en","type":"article","venue":"Sultan Qaboos University medical journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; University of Saskatchewan; McGill University Health Centre","funders":"","keywords":"Chimeric antigen receptor; Medicine; Immunotherapy; Antigen; Receptor; Immunology; Antigen-presenting cell; T cell; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001235948,0.000249843,0.0003766521,0.0003663897,0.0001932705,0.0008945939,0.0002623696,0.0007868973,0.001611554],"category_scores_gemma":[0.0004330662,0.0001313097,0.0001869557,0.0002688207,0.0006982819,0.0007896346,0.0003515634,0.0008571306,0.0003501335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004851507,"about_ca_system_score_gemma":0.0007050884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002573691,"about_ca_topic_score_gemma":0.0004563409,"domain_scores_codex":[0.9997955,0.00007755969,0.00001188885,0.0000211452,0.00006472201,0.00002915859],"domain_scores_gemma":[0.9998492,0.00008003951,0.00002703138,0.000007139804,0.00002004836,0.00001654961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000636376,0.0005999185,0.003579009,0.002126902,0.00003433996,0.0008157148,0.0004782188,0.001932629,0.2291488,0.02732282,0.003156206,0.7301691],"study_design_scores_gemma":[0.0009060591,0.01303257,0.008414865,0.001383981,0.0002072638,0.01237893,0.000986842,0.006965986,0.3989942,0.03122992,0.5254003,0.00009912265],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.283575,0.6212116,0.05725302,0.01779582,0.0004406535,0.0003486265,0.00006820976,0.0002544379,0.01905251],"genre_scores_gemma":[0.6552597,0.2984505,0.03549697,0.00350564,0.0006068997,0.0001949236,0.0001046341,0.00005350991,0.006327217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001611554,"threshold_uncertainty_score":0.006536365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06018600695271235,"score_gpt":0.3941796720039296,"score_spread":0.3339936650512172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}