{"id":"W4413223210","doi":"10.3390/curroncol32080448","title":"Recent Advances in the Management of EGFR-Mutated Advanced Non-Small Cell Lung Cancer—A Narrative Review","year":2025,"lang":"en","type":"review","venue":"Current Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Western University; Princess Margaret Cancer Centre; NOSM University; McGill University; Health Sciences North","funders":"","keywords":"Medicine; Osimertinib; Oncology; Lung cancer; Regimen; Bevacizumab; Clinical trial; Internal medicine; Epidermal growth factor receptor; Cancer; Erlotinib; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005575122,0.0007069369,0.00110539,0.002191132,0.0002363083,0.001024383,0.0008105086,0.0007457607,0.004486278],"category_scores_gemma":[0.001075236,0.0001955745,0.0006698744,0.001967479,0.000285729,0.001163971,0.0006445656,0.001449423,0.001444082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005051786,"about_ca_system_score_gemma":0.001046859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009643,"about_ca_topic_score_gemma":0.00188113,"domain_scores_codex":[0.999819,0.00003880101,0.00003491493,0.00003086446,0.00005947839,0.00001693549],"domain_scores_gemma":[0.9995145,0.0002917808,0.00007596989,0.00000889628,0.00008157082,0.0000271711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006683452,0.00005067419,0.0001160466,0.03750738,0.0001042034,0.0001380919,0.00005817814,0.0003148481,0.0004909662,0.001974777,0.02445555,0.9347224],"study_design_scores_gemma":[0.0000232244,0.0001075395,0.0006550532,0.01593521,0.0002740966,0.001219803,0.00008248172,0.0001011488,0.0001711994,0.001462697,0.9799489,0.00001857283],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006140099,0.9989966,0.0000543965,0.0002147504,0.0001294226,0.000004059099,0.00001363835,0.00000431602,0.000521476],"genre_scores_gemma":[0.0003646112,0.9990523,0.0001123007,0.0001495925,0.0001224966,0.000004384759,0.00002219065,9.229365e-7,0.0001710564],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004486278,"threshold_uncertainty_score":0.01500815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06341274929620676,"score_gpt":0.5037685852525103,"score_spread":0.4403558359563036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}