{"id":"W4413229376","doi":"10.1016/j.brci.2025.100020","title":"GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells","year":2025,"lang":"en","type":"article","venue":"Blood Red Cells & Iron","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"GPX4; Lipid peroxidation; Cell biology; Chemistry; Biology; Biochemistry; Antioxidant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224219,0.0002890741,0.0001756493,0.0002323115,0.0002679604,0.0004125379,0.0001571404,0.0002721481,0.001728585],"category_scores_gemma":[0.0003148096,0.0001240146,0.0003035343,0.0001865613,0.0001908943,0.0001504325,0.0004179964,0.0003385346,0.0002408837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003124228,"about_ca_system_score_gemma":0.0002409788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00117203,"about_ca_topic_score_gemma":0.0008932758,"domain_scores_codex":[0.9998839,0.00002686309,0.000007322435,0.00003169402,0.00002701266,0.00002320428],"domain_scores_gemma":[0.9998792,0.00001346106,0.00005505314,0.000009698506,0.00002339703,0.00001912402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001674748,0.00009302504,0.06453317,0.0003698067,0.0003811059,0.0006971358,0.0002277835,0.0009025053,0.8911458,0.001672711,0.002864112,0.03543806],"study_design_scores_gemma":[0.0002597107,0.0006666684,0.4630622,0.0001210168,0.0005532586,0.002819326,0.000355876,0.005712452,0.4948039,0.003086129,0.02851469,0.00004477779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904603,0.004708543,0.002131673,0.0003262102,0.00006061932,0.00002210504,0.0008029872,0.0001218073,0.001365802],"genre_scores_gemma":[0.9942337,0.001664168,0.0008296567,0.00009839519,0.00001966787,0.00001817407,0.0007714077,0.00002170312,0.002343077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001728585,"threshold_uncertainty_score":0.005782723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003870674467197719,"score_gpt":0.2057653413559185,"score_spread":0.2018946668887207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}