{"id":"W4413242465","doi":"10.21203/rs.3.rs-7235912/v1","title":"Pediatric Hemophagocytic Lymphohistiocytosis Presenting as a Refractory Febrile Illness: A CASE REPORT","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Continental (Canada)","funders":"","keywords":"Hemophagocytic lymphohistiocytosis; Hepatosplenomegaly; Medicine; Organomegaly; Pallor; Pediatrics; Cytopenia; Pancytopenia; Fever of unknown origin; Hypofibrinogenemia; Internal medicine; Bone marrow; Polyneuropathy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005080778,0.004105425,0.002430073,0.004033443,0.003728791,0.002741953,0.001912532,0.009928331,0.004349087],"category_scores_gemma":[0.003486239,0.002337426,0.001999677,0.002383693,0.003371522,0.003373328,0.002318648,0.004591718,0.001999245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002166527,"about_ca_system_score_gemma":0.001376475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002381939,"about_ca_topic_score_gemma":0.002152993,"domain_scores_codex":[0.9988997,0.0001125181,0.0001111373,0.0003292101,0.0001369444,0.0004105075],"domain_scores_gemma":[0.9974899,0.0008972109,0.0003654415,0.0002373055,0.0001142097,0.0008959848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00001842803,0.00002376652,0.00139485,0.00001817109,0.000003663361,0.9977446,0.00005839739,0.00002904396,0.0002050013,0.00007596848,0.00009786366,0.0003303129],"study_design_scores_gemma":[0.00001489103,0.00003967172,0.002278348,0.0000106286,0.00001479802,0.996828,0.00009901728,0.0001186414,0.0002217597,0.0001013184,0.0002616447,0.00001126529],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562637,0.01177097,0.006065826,0.004159254,0.0009318139,0.0005472291,0.0009436213,0.0004567014,0.01886092],"genre_scores_gemma":[0.9886247,0.003569063,0.002119802,0.0009325173,0.002524181,0.00006646052,0.0002675918,0.00006384464,0.001831959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009928331,"threshold_uncertainty_score":0.01571929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05046327348618241,"score_gpt":0.4113307280895564,"score_spread":0.360867454603374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}