{"id":"W4413280815","doi":"10.26508/lsa.202402820","title":"Dysregulated <i>SASS6</i> expression promotes increased ciliogenesis and cell invasion phenotypes","year":2025,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Institute; National Human Genome Research Institute; Johns Hopkins University; Biotechnology and Biological Sciences Research Council; Medical Research Council; University of Liverpool; University of Oxford; European Research Council; Kidney Research UK; King's College London; UK Research and Innovation; June Hancock Mesothelioma Research Fund; Worldwide Cancer Research","keywords":"Ciliogenesis; Phenotype; Biology; Expression (computer science); Cell biology; Genetics; Cilium; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001789573,0.0001364292,0.0001130067,0.00004573144,0.000240619,0.00006996813,0.0002944971,0.00007337865,0.00001082411],"category_scores_gemma":[0.0002635856,0.000115312,0.00003363422,0.0003436216,0.0003835227,0.00001631415,0.0002215155,0.00004330876,0.000005594747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009023322,"about_ca_system_score_gemma":0.0002854067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003132724,"about_ca_topic_score_gemma":0.000006618856,"domain_scores_codex":[0.9988165,0.0000325197,0.0001541682,0.000540199,0.0001922024,0.0002644214],"domain_scores_gemma":[0.9992653,0.00001591185,0.00006069295,0.000362874,0.00009562563,0.0001996481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005218933,0.00005171143,0.01673796,0.00004575887,0.000003350232,0.000001629367,0.00001306379,0.00002725467,0.9812521,0.00005401129,0.001089543,0.0006714464],"study_design_scores_gemma":[0.0004374674,0.00004715699,0.01977498,0.00007828305,0.00001147833,8.728477e-7,0.00004261299,0.0003245944,0.9768791,0.0001246564,0.002133838,0.000144918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936229,0.003019503,0.0002384902,0.0002013662,0.0001038048,0.0001748053,0.00001041312,0.00001925702,0.002609485],"genre_scores_gemma":[0.9970725,0.0005304488,0.001043885,0.0006711953,0.00003787319,0.00002120328,0.0000145942,0.000006769835,0.0006015506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004372939,"threshold_uncertainty_score":0.4702288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005679400859638601,"score_gpt":0.2317509955206805,"score_spread":0.2260715946610419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}