{"id":"W4413282660","doi":"10.3390/curroncol32080469","title":"Pembrolizumab-Induced Simultaneous and Refractory Systemic Capillary Leak and Cytokine Release Syndromes: A Case Report","year":2025,"lang":"en","type":"article","venue":"Current Oncology","topic":"Muscle and Compartmental Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec; Université Laval","funders":"","keywords":"Medicine; Pembrolizumab; Anasarca; Adverse effect; Internal medicine; Tocilizumab; Nivolumab; Cancer; Immunotherapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000133958,0.0002099999,0.0005445099,0.000175077,0.0001181632,0.00001296365,0.00004669344,0.0001533292,0.00003356232],"category_scores_gemma":[0.0002527042,0.0001887289,0.00005803291,0.0001503294,0.0001233813,0.00004445759,0.0001046107,0.000316584,0.000009366438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002293851,"about_ca_system_score_gemma":0.0002890072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009875534,"about_ca_topic_score_gemma":0.0001116117,"domain_scores_codex":[0.998627,0.00009999902,0.0004262413,0.0004550646,0.0001198112,0.0002718666],"domain_scores_gemma":[0.9990074,0.0002315752,0.0001325779,0.0003317338,0.00008145304,0.0002152648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.002145365,0.002623719,0.03714197,0.005041955,0.0005733955,0.5372899,0.001564651,0.000009738255,0.01215346,0.0006722008,0.01088913,0.3898945],"study_design_scores_gemma":[0.01146377,0.002964625,0.008118898,0.001272551,0.0009506656,0.7921066,0.003947873,0.002604948,0.0002224236,0.0001878737,0.1756231,0.0005366264],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813883,0.01397978,0.00002549154,0.0004427196,0.0006700683,0.0006190576,0.000008179431,0.00008135449,0.002784991],"genre_scores_gemma":[0.9977564,0.001356561,0.00001697965,0.0002463104,0.00006595811,0.00005856451,0.00004642897,0.0000158884,0.0004369441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3893579,"threshold_uncertainty_score":0.7696143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06095739337967425,"score_gpt":0.3822193230639082,"score_spread":0.3212619296842339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}