{"id":"W4413282698","doi":"10.3390/curroncol32080467","title":"Targeting Senescence in Oncology: An Emerging Therapeutic Avenue for Cancer","year":2025,"lang":"en","type":"review","venue":"Current Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Senescence; Cancer; Medicine; Cancer research; Cancer cell; Cancer prevention; Immunology; Bioinformatics; Oncology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008398279,0.0008539899,0.001364972,0.001953358,0.0003558012,0.001028111,0.000836877,0.001583744,0.004348435],"category_scores_gemma":[0.000805867,0.0002213892,0.0005935749,0.001638383,0.0007266278,0.001923438,0.0008117848,0.003326047,0.001705265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007689239,"about_ca_system_score_gemma":0.001252405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008081857,"about_ca_topic_score_gemma":0.001766563,"domain_scores_codex":[0.9997723,0.00005691816,0.00002248641,0.00003431974,0.00008403283,0.00002992308],"domain_scores_gemma":[0.9995346,0.0002413593,0.00004395333,0.00001501038,0.0001122951,0.00005277594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009006545,0.0001098037,0.0001253607,0.01552705,0.00007659495,0.0001801727,0.00008421653,0.0004207874,0.002033133,0.008675415,0.04518146,0.927496],"study_design_scores_gemma":[0.00002132596,0.0001352707,0.0003914542,0.003168807,0.00007583079,0.0007276532,0.00005768451,0.00009722177,0.0002750828,0.003583843,0.991451,0.00001490303],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006565511,0.9984037,0.0001144469,0.0005278387,0.0002927623,0.000003203088,0.00000782916,0.000007729274,0.0005768345],"genre_scores_gemma":[0.0004662187,0.9982761,0.000152518,0.0004223869,0.0002721539,0.000005588465,0.00001711279,0.00000137833,0.0003865693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004348435,"threshold_uncertainty_score":0.01454693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2718485443707056,"score_gpt":0.5357803837700843,"score_spread":0.2639318393993787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}