{"id":"W4413325769","doi":"10.1016/j.neuron.2025.07.024","title":"Microglia regulate neuronal activity via structural remodeling of astrocytes","year":2025,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Heart and Stroke Foundation of Canada","keywords":"Microglia; Neuroscience; Astrocyte; Premovement neuronal activity; Neuroinflammation; Biology; Cell biology; Inflammation; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008176028,0.0001991887,0.0002106718,0.0001920419,0.0001886697,0.00005176943,0.0002949706,0.00005714088,0.00006039677],"category_scores_gemma":[0.0002274969,0.0002003191,0.0001015543,0.0003521946,0.00007833287,0.000254299,0.0001210051,0.0002478178,0.00001855712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001817397,"about_ca_system_score_gemma":0.00005382691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004353016,"about_ca_topic_score_gemma":0.000002659114,"domain_scores_codex":[0.9982958,0.0002497406,0.0003389889,0.0005493494,0.0003073415,0.0002587169],"domain_scores_gemma":[0.9991439,0.000156028,0.0001817697,0.0003988508,0.00005603679,0.00006341137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001017204,0.00001921509,0.00003244071,0.00002238985,0.00000117891,0.000005301883,0.00001672408,0.001504039,0.9883428,0.003547002,0.00009200792,0.006315233],"study_design_scores_gemma":[0.0003749512,0.00008104445,0.002222007,0.0000108281,0.000009112368,0.00001679497,0.000001258648,0.04882281,0.947123,0.0006862021,0.0005410279,0.0001109775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924132,0.00000638757,0.004839208,0.0006045518,0.0008997564,0.0002307018,0.00001131272,0.0001518285,0.0008430283],"genre_scores_gemma":[0.997216,0.00001254808,0.0003862578,0.001150836,0.00004846375,0.00000515622,0.000001589055,0.00002161114,0.00115753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04731877,"threshold_uncertainty_score":0.8168774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02100360826679762,"score_gpt":0.2679533916872253,"score_spread":0.2469497834204277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}