{"id":"W4413344798","doi":"10.1016/j.jdermsci.2025.08.003","title":"Granzyme K contributes to acute itch in psoriasis","year":2025,"lang":"en","type":"letter","venue":"Journal of Dermatological Science","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Coastal Health Research Institute; International Collaboration On Repair Discoveries; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Osaka Medical Research Foundation for Intractable Diseases; Lydia O'Leary Memorial Pias Dermatological Foundation","keywords":"Psoriasis; Granzyme B; Medicine; Dermatology; Immunology; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001005026,0.0005300246,0.0008294485,0.0005713315,0.001643515,0.001847236,0.0007065136,0.01382937,0.004112714],"category_scores_gemma":[0.00744253,0.0003905759,0.0007182115,0.000364432,0.001352994,0.001795951,0.0009268404,0.009407273,0.00212183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001734995,"about_ca_system_score_gemma":0.0008026256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001929478,"about_ca_topic_score_gemma":0.002100481,"domain_scores_codex":[0.9992896,0.0002463839,0.0001054355,0.000066318,0.0001265158,0.0001657266],"domain_scores_gemma":[0.9976234,0.001461221,0.0001803546,0.0001274452,0.0002393726,0.0003681505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001458564,0.0002863789,0.03069559,0.0003432593,0.00009971789,0.4858625,0.0007086844,0.0003416414,0.002442316,0.009972521,0.4258148,0.04197401],"study_design_scores_gemma":[0.002274857,0.0005860206,0.03591128,0.001047249,0.0002323679,0.5625407,0.002594115,0.005635297,0.001456976,0.04708606,0.3405037,0.0001314252],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.04804512,0.01231866,0.0006009492,0.891186,0.01767962,0.00006147965,0.00009324223,0.0001064317,0.02990844],"genre_scores_gemma":[0.5244123,0.007489508,0.0008427002,0.3056021,0.1415964,0.0000554407,0.00009976767,0.00005409675,0.01984775],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01382937,"threshold_uncertainty_score":0.01375842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152689967561712,"score_gpt":0.3165700679448338,"score_spread":0.3013010711886626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}