{"id":"W4413357753","doi":"10.2196/71494","title":"Tenofovir to Prevent HIV Infection in Western China: Pragmatic Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"JMIR Public Health and Surveillance","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Emtricitabine; Randomized controlled trial; Pre-exposure prophylaxis; Regimen; Adverse effect; Population; Clinical trial; Men who have sex with men; Internal medicine; Family medicine; Human immunodeficiency virus (HIV); Viral load; Environmental health; Antiretroviral therapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009675817,0.002287748,0.005976233,0.0009900442,0.000922333,0.00107508,0.0009957042,0.002517442,0.006415473],"category_scores_gemma":[0.008301846,0.0008564909,0.003946988,0.001304822,0.001391365,0.001262304,0.001027266,0.001381161,0.0003286263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002470694,"about_ca_system_score_gemma":0.005746055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003568077,"about_ca_topic_score_gemma":0.006008068,"domain_scores_codex":[0.9923286,0.005396009,0.0007813855,0.0006374904,0.0003936269,0.0004629534],"domain_scores_gemma":[0.9969946,0.0007656832,0.0009234186,0.000236631,0.0003448645,0.0007347486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.919699,0.01057423,0.003343372,0.01263113,0.008557327,0.0001790692,0.000225089,0.0005170633,0.0009119766,0.0004246743,0.001113852,0.04182319],"study_design_scores_gemma":[0.9619561,0.02986569,0.002608917,0.0004953836,0.003414115,0.00003567576,0.00005533992,0.0004720986,0.0001010953,0.0002991582,0.0006711076,0.00002531033],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8646924,0.04400922,0.003035356,0.00271134,0.002016197,0.07793298,0.001449291,0.0001924599,0.003960615],"genre_scores_gemma":[0.9294938,0.007527155,0.005128253,0.003029146,0.0005689594,0.05230276,0.0005611726,0.00001362505,0.001375079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009675817,"threshold_uncertainty_score":0.05117124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157489758792743,"score_gpt":0.3635097504705344,"score_spread":0.3477607745912601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}