{"id":"W4413471140","doi":"10.22541/au.175593247.76283357/v1","title":"AAV Assembled Capsids Are Produced in Cells Blocked from Cell Cycle Progression.","year":2025,"lang":"en","type":"article","venue":"","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; National Research Council Canada","funders":"","keywords":"Capsid; Cell cycle progression; Cell biology; Cell; Cell cycle; Virology; Chemistry; Computer science; Virus; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004086742,0.0003484159,0.0004628738,0.0002748068,0.0003171213,0.0008117015,0.0003068492,0.0003850776,0.001078099],"category_scores_gemma":[0.0006452352,0.0003185011,0.0003532469,0.000270913,0.0003324109,0.0004265842,0.0003596843,0.0008756283,0.001300021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004539138,"about_ca_system_score_gemma":0.0003630337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001348609,"about_ca_topic_score_gemma":0.001855819,"domain_scores_codex":[0.9994463,0.00008625547,0.00005321825,0.0001452785,0.0001986793,0.00007010561],"domain_scores_gemma":[0.9996415,0.00008204824,0.0001030571,0.00005995803,0.00007004345,0.00004332468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005336377,0.00001385148,0.0003585,0.00005517061,0.000008187173,0.0000358293,0.00005080268,0.00006276873,0.9966396,0.0002238872,0.0001428735,0.002355137],"study_design_scores_gemma":[0.0000118203,0.0001847686,0.005045034,0.00001518445,0.00001979794,0.0002778622,0.00004175649,0.001196643,0.9762769,0.000203452,0.01671222,0.00001439195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8609477,0.007092813,0.116616,0.0002427809,0.0004033097,0.0004343524,0.003406268,0.0012639,0.00959282],"genre_scores_gemma":[0.8991238,0.003268208,0.06677274,0.0003171883,0.00004398965,0.0005436848,0.01023979,0.0005851716,0.01910557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001348609,"threshold_uncertainty_score":0.003606617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009044186789070137,"score_gpt":0.3023047430796146,"score_spread":0.2932605562905445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}