{"id":"W4413573099","doi":"10.64628/aap.755kh59p7","title":"FDA approval of controversial Alzheimer’s drug could delay discovery of more promising treatments","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Drug discovery; Drug; Drug approval; Medicine; Pharmacology; Internet privacy; Business; Computer science; Biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01263514,0.0005034457,0.0009988182,0.001663134,0.0006435752,0.004657906,0.0005842739,0.004875015,0.01959736],"category_scores_gemma":[0.06064988,0.0003191089,0.0005536611,0.001104024,0.001575499,0.004543139,0.001067526,0.003258899,0.001200403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003210312,"about_ca_system_score_gemma":0.003491818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002460788,"about_ca_topic_score_gemma":0.002197485,"domain_scores_codex":[0.995401,0.002845831,0.000199071,0.0004155324,0.0008251962,0.0003133403],"domain_scores_gemma":[0.9463229,0.04423791,0.003936111,0.001780353,0.002844343,0.000878532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000876701,0.0001499756,0.005496118,0.000370496,0.0002033462,0.0001873127,0.00009434515,0.008104174,0.0004705387,0.8065,0.08497083,0.09257616],"study_design_scores_gemma":[0.0003086251,0.0001048232,0.004236974,0.0001467748,0.0001135355,0.0001348337,0.000109005,0.01828586,0.0008019828,0.9313111,0.04441676,0.00002977716],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1170832,0.02334319,0.1125017,0.4450219,0.009498826,0.0002655208,0.004435455,0.0007678827,0.2870824],"genre_scores_gemma":[0.928939,0.004630126,0.01619727,0.01192612,0.005365166,0.0001374706,0.0007175829,0.0001524841,0.03193495],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01959736,"threshold_uncertainty_score":0.06682181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3337293971336487,"score_gpt":0.433161890485099,"score_spread":0.09943249335145027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}