{"id":"W4413576393","doi":"10.1007/s00705-025-06369-4","title":"The mechanism of action of micafungin against pteropine orthoreovirus infection in the human A549 cell line","year":2025,"lang":"en","type":"article","venue":"Archives of Virology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Nagoya University","keywords":"Biology; Syncytium; Viral replication; Virology; Virus; Gene silencing; Mechanism of action; Messenger RNA; Cell culture; Gene; Microbiology; Genetics; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004101592,0.00008101446,0.0003222101,0.0002236777,0.00004797717,0.000001299872,0.0001561685,0.00005964341,0.00001113378],"category_scores_gemma":[0.0001973805,0.00004949348,0.0001080862,0.0001255462,0.0004253071,0.00001623334,0.00007722739,0.000269311,8.571011e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007685374,"about_ca_system_score_gemma":0.00003087498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004709372,"about_ca_topic_score_gemma":0.0007973062,"domain_scores_codex":[0.9986234,0.0004930694,0.0004453837,0.0001337024,0.00008352905,0.0002208992],"domain_scores_gemma":[0.9992552,0.0002682536,0.000161239,0.0002671845,0.0000230909,0.00002504621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007814715,0.0002552813,0.0405897,0.0001568662,0.00005280602,0.000005872931,0.000168048,0.00004299597,0.9392005,0.004899327,0.0001252801,0.01372181],"study_design_scores_gemma":[0.002551901,0.005132895,0.8066759,0.0001748154,0.00006252807,0.00001671657,0.0002241247,0.001557787,0.1679265,0.01359827,0.002011127,0.00006742222],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933008,0.0001994439,0.001764636,0.001786124,0.00006701078,0.0002676776,0.00000978843,0.000005217157,0.002599301],"genre_scores_gemma":[0.9970774,0.002188357,0.0002191856,0.0003212943,0.00002921307,0.00001905988,0.00002717441,0.000004863995,0.0001134445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.771274,"threshold_uncertainty_score":0.2018286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02603239712731166,"score_gpt":0.345079980246115,"score_spread":0.3190475831188033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}