{"id":"W4413683564","doi":"10.1001/jamanetworkopen.2025.28907","title":"Poststroke Cardiorespiratory Exercise for Brain Volume and Cognition","year":2025,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Stroke Rehabilitation and Recovery","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; National Institutes of Health; Medtronic; Medical Research Council; Bayer; Australian Football League; Eli Lilly and Company; AtriCure; F. Hoffmann-La Roche; Dementia Australia; Alzheimer's Drug Discovery Foundation; Roche; Novo Nordisk; Eisai; Abbott Laboratories","keywords":"Medicine; Cardiorespiratory fitness; Physical therapy; Randomized controlled trial; Stroke (engine); Montreal Cognitive Assessment; Cognition; Aerobic exercise; Intervention (counseling); Physical medicine and rehabilitation; Internal medicine; Psychiatry; Cognitive impairment","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001536349,0.0005342295,0.0005916175,0.0002139361,0.0003217873,0.0003854596,0.0003978769,0.0005899292,0.004622988],"category_scores_gemma":[0.001354992,0.0001358699,0.0004576657,0.0002829671,0.0003186378,0.0002019836,0.000288456,0.0005949305,0.0003667991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000264059,"about_ca_system_score_gemma":0.0009472643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006401403,"about_ca_topic_score_gemma":0.002342461,"domain_scores_codex":[0.9993194,0.0003945229,0.00005511706,0.00006443727,0.00008440758,0.00008199271],"domain_scores_gemma":[0.9995467,0.0001438499,0.000130914,0.00002950385,0.00005662349,0.00009235905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4496583,0.04300913,0.03754214,0.0080819,0.002676046,0.0001126217,0.0002425105,0.0009911414,0.01781747,0.0007076802,0.006614018,0.4325471],"study_design_scores_gemma":[0.3210528,0.3347591,0.3176745,0.001033056,0.002504329,0.0001637187,0.0001654438,0.001689522,0.006459129,0.0007462417,0.01370751,0.00004460698],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738756,0.008599753,0.001115353,0.0009896086,0.000345279,0.008355374,0.000891929,0.00007531499,0.005751773],"genre_scores_gemma":[0.9873431,0.002345494,0.001699756,0.0004461856,0.0002568447,0.005200218,0.0004014363,0.000004654437,0.002302314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004622988,"threshold_uncertainty_score":0.01546544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01384621971752753,"score_gpt":0.3050653920206663,"score_spread":0.2912191723031388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}