{"id":"W4413683564","doi":"10.1001/jamanetworkopen.2025.28907","title":"Poststroke Cardiorespiratory Exercise for Brain Volume and Cognition","year":2025,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Stroke Rehabilitation and Recovery","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; National Institutes of Health; Medtronic; Medical Research Council; Bayer; Australian Football League; Eli Lilly and Company; AtriCure; F. Hoffmann-La Roche; Dementia Australia; Alzheimer's Drug Discovery Foundation; Roche; Novo Nordisk; Eisai; Abbott Laboratories","keywords":"Medicine; Cardiorespiratory fitness; Physical therapy; Randomized controlled trial; Stroke (engine); Montreal Cognitive Assessment; Cognition; Aerobic exercise; Intervention (counseling); Physical medicine and rehabilitation; Internal medicine; Psychiatry; Cognitive impairment","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005866694,0.00009571482,0.000301963,0.0000672178,0.0001097611,0.0001001053,0.00008364659,0.0001157295,0.00006060647],"category_scores_gemma":[0.0002883496,0.00008503306,0.00009980742,0.0001571827,0.00005629918,0.0001316283,0.00009368922,0.0001036742,0.00001452596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003553241,"about_ca_system_score_gemma":0.0001166257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001477069,"about_ca_topic_score_gemma":0.000005819753,"domain_scores_codex":[0.9992519,0.00005681444,0.0001968088,0.0002288646,0.00008276665,0.0001828188],"domain_scores_gemma":[0.9992187,0.0003469558,0.00004562081,0.0001758942,0.0001286615,0.00008417026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001849792,0.00006520424,0.1585602,0.0002887934,0.0001752756,0.000005986158,0.0001160333,0.00003830391,0.0003002736,0.0009304494,0.6508103,0.1868594],"study_design_scores_gemma":[0.004431167,0.0002908322,0.530629,0.001007919,0.0002131422,0.000006359056,0.0002293598,0.0006946074,0.00009423205,0.00101429,0.4612652,0.0001238617],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8589667,0.008528695,0.004071272,0.03488699,0.00173061,0.007987291,0.0001010218,0.0001322317,0.08359519],"genre_scores_gemma":[0.9386888,0.0002806702,0.006221781,0.01373564,0.0009371875,0.0005709465,0.0001353762,0.00003270851,0.03939691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3720689,"threshold_uncertainty_score":0.3467548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01384621971752753,"score_gpt":0.3050653920206663,"score_spread":0.2912191723031388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}