{"id":"W4413704967","doi":"10.2196/76783","title":"Comparative Evaluation of the Antibacterial Efficacy of Metronidazole, Chlorhexidine, and Normal Saline as Laser- and Sonic-Activated Intracanal Irrigants Against Enterococcus faecalis: In Vitro Study Protocol","year":2025,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Endodontics and Root Canal Treatments","field":"Dentistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Enterococcus faecalis; Chlorhexidine; Metronidazole; Saline; Dentistry; Preprint; Medicine; Microbiology; Staphylococcus aureus; Biology; Antibiotics; World Wide Web; Computer science; Bacteria","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001553515,0.0006854564,0.0008873909,0.0004706613,0.0002927068,0.0004706046,0.0006152894,0.0005649049,0.00189526],"category_scores_gemma":[0.001042248,0.0003733558,0.000845753,0.0005397635,0.000422845,0.000369925,0.000377046,0.0005146818,0.0002926021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002698324,"about_ca_system_score_gemma":0.0008772166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006220932,"about_ca_topic_score_gemma":0.001222757,"domain_scores_codex":[0.9984928,0.0003921792,0.0003706529,0.0002501521,0.0003840869,0.0001101104],"domain_scores_gemma":[0.9983315,0.0005606589,0.0003006981,0.0001280338,0.0005754681,0.0001036602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004030053,0.002074232,0.001366271,0.0009009594,0.00005856018,0.0001222448,0.0002452389,0.0002396987,0.9843888,0.00009002066,0.00007862261,0.006405215],"study_design_scores_gemma":[0.0005186373,0.08032269,0.01445632,0.0001318228,0.0005885984,0.0005366876,0.0004953679,0.0007151341,0.8978313,0.00008807165,0.00424374,0.00007164676],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9920101,0.00431597,0.001632046,0.00004649204,0.00009332625,0.0007039722,0.00032488,0.00001377831,0.0008594969],"genre_scores_gemma":[0.9656197,0.007660679,0.02095509,0.00009992518,0.00009724675,0.001992129,0.0009996813,0.00001494893,0.002560528],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.00189526,"threshold_uncertainty_score":0.008215904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1641073265404744,"score_gpt":0.540528418128319,"score_spread":0.3764210915878446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}