{"id":"W4413726990","doi":"10.3389/jpps.2025.14614","title":"Optimized Ginkgo biloba extract EGb 761®: boosted therapeutic benefits with minimized CYP enzyme interference","year":2025,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Ginkgo biloba and Cashew Applications","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; National Research Foundation","keywords":"Ginkgo biloba; Pharmacology; Interference (communication); Ginkgo; Cytochrome P450; Chemistry; Enzyme; Medicine; Traditional medicine; Biochemistry; Computer science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000878333,0.0004712662,0.0003142099,0.0005936123,0.0001279346,0.0002855893,0.0001400052,0.0002200816,0.001649515],"category_scores_gemma":[0.00012759,0.00009574522,0.0002276208,0.0002883397,0.0001367511,0.0002702693,0.0002153164,0.0004558199,0.0003119421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774625,"about_ca_system_score_gemma":0.0001629122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004734954,"about_ca_topic_score_gemma":0.001059206,"domain_scores_codex":[0.9999499,0.000008391396,0.000003540362,0.00001124565,0.00001622115,0.00001065193],"domain_scores_gemma":[0.9999685,0.000004769503,0.00001016482,0.000002336178,0.00000631093,0.000007908156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005599938,0.0001045229,0.0002428491,0.0002983332,0.00003220843,0.00007998552,0.00001301524,0.0002304489,0.9873712,0.0001515031,0.0001380952,0.0107778],"study_design_scores_gemma":[0.00009561863,0.001093424,0.008354591,0.00005473929,0.0001978124,0.0004187885,0.00004295127,0.0009976694,0.9758736,0.0002165999,0.01262753,0.00002670392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789304,0.00970688,0.005364632,0.0002441929,0.00006937928,0.0001000957,0.001158369,0.0001409982,0.004284962],"genre_scores_gemma":[0.9853635,0.003445549,0.00683284,0.0001860755,0.00001560696,0.00004624916,0.000761195,0.00005782237,0.003291057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001649515,"threshold_uncertainty_score":0.005518198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0824731711930164,"score_gpt":0.4114996205682835,"score_spread":0.3290264493752671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}